| Japanese |
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| Title | 123I-MIBG心筋シンチグラフィによる心筋への集積を認めず, 内科的治療によって集積の改善を認めた冠攣縮性狭心症の1例 |
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| Subtitle | 症例報告 |
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| Authors | 渡辺浩毅*, 鶴岡高志*, 関谷達人***, 舩田淳一***, 中川裕章** |
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| Organization | *愛媛県立南宇和病院内科, **愛媛県立南宇和病院放射線科, ***国立療養所愛媛病院循環器科 |
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| Journal | 核医学 |
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| Volume | 35 |
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| Number | 8 |
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| Page | 727-732 |
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| Year/Month | 1998/10 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 症例は68歳女性. 平成6年11月頃より全身倦怠感を自覚していた. 平成7年1月より夜間の前胸部痛を自覚するようになり, 狭心症の疑いで2月14日に入院した. 血圧・脈拍正常で血液・生化学検査にも異常なく, 体液性因子も正常範囲であった. 耐糖能は正常で, 神経学的異常を認めなかった. 冠動脈造影では器質的狭窄を認めず, Ach負荷によって3枝ともに瀰漫性の冠攣縮を認めた. ATP負荷201Tl心筋SPECTおよび安静時123I-BMIPP SPECTでは正常な集積を認めたが, 安静時123I-MIBG心筋シンチでは心筋への集積を認めず, 冠攣縮性狭心症が原因でMIBGの無集積をきたしたものと考えられた. 冠拡張剤とCa拮抗剤の投与による自覚症状の改善に伴い, MIBGの集積は軽度改善した. これまでにMIBG無集積の報告は散見されるが冠攣縮性狭心症が無集積の原因で, かつ薬物治療により改善を見たとの報告はないので報告する. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-MIBG, Vasospastic angina, Therapeutic effect |
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| English |
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| Title | Markedly Decreased Uptake with 123I-MIBG Myocardial Scintigraphy in a Case with Vasospastic Angina |
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| Subtitle | |
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| Authors | Kouki WATANABE*, Takashi TSURUOKA*, Michihito SEKIYA**, Junichi FUNADA**, Hiroaki NAKAGAWA* |
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| Authors(kana) | |
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| Organization | *Division of Cardiology and Radiology, Ehime Prefectural Minamiuwa Hospital, **Department of Cardiology, Ehime National Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 35 |
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| Number | 8 |
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| Page | 727-732 |
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| Year/Month | 1998/10 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] A 68-year-old female whose myocardial sympathetic function was severely damaged with multi-vessel vasospastic angina is presented. She had no signs of autonomic dysfunction or diabetes mellitus. Myocardial imaging with 123I-MIBG showed extremely diminished uptake, but 201TlCl and 123I-BMIPP SPECT images were almost normal. Coronary arteriography revealed no significant atherosclerotic stenosis, multi-vessel spasm was observed by provocation test using acetylcholine. The extremely diminished uptake of 123I-MIBG was slightly increased in response to medication and the subsequent improvement of the patient's condition. Markedly decreased uptake with 123I-MIBG myocardial scintigraphy was considered to be due to multi-vessel spastic angina. We believe that this method of imaging study is useful for evaluating the healing stage of myocardial sympathetic dysfunction. |
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| Practice | Clinical medicine |
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| Keywords | 123I-MIBG, Vasospastic angina, Therapeutic effect |
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