Japanese
Title99mTc標識心筋血流製剤を用いた初回循環時法による心拍出量の推定法
Subtitle原著
Authors村守朗*, 滝淳一*, 絹谷清剛*, 宮崎吉春**, 中嶋憲一*, 松成一朗*, 利波紀久*
Authors(kana)
Organization*金沢大学医学部核医学科, **公立能登総合病院中央放射線部
Journal核医学
Volume35
Number5
Page273-279
Year/Month1998/6
Article原著
Publisher日本核医学会
Abstract「要旨」99mTc-Tetrofosmin (以下TFM) を用いて正面よりRIアンギオグラフィを行い, 心室に設定したROIの初回循環時の積算カウントおよび胸部全体に設定したROIの最高カウントを求めることにより, 投与前のRI量測定や平衡時データ収集を省略して心拍出量(CO)を簡便に推定する指標(COI)の算出を試みた. COI(y)は同時期に行った従来の Stewart-Hamilton 法より算出したCO(x)と良好な相関を示し(y = 0.0381x + 6.22, r = 0.828, n = 48, p < 0.001), COを精度よく推定することが可能であった. 本法により心筋血流イメージング製剤にて, 同時にCO算出が可能になった.
Practice臨床医学:一般
KeywordsCardiac output, Radionuclide, First-pass study, Cardiac output index, Tetrofosmin
English
TitleEstimation of Cardiac Output by First-Pass Data with Technetium-99m-labeled Myocardial Perfusion Imaging Agent
SubtitleOriginal Articles
AuthorsAkira MURAMORI*, Junichi TAKI*, Seigo KINUYA*, Yoshiharu MIYAZAKI**, Kenichi NAKAJIMA*, Ichiro MATSUNARI*, Norihisa TONAMI*
Authors(kana)
Organization*Department of Nuclear Medicine, Kanazawa University School of Medicine, **Section of Nuclear Medicine, Noto General Hospital
JournalThe Japanese Journal of nuclear medicine
Volume35
Number5
Page273-279
Year/Month1998/6
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractTechnetium-99m-tetrofosmin, a myocardial perfusion imaging agent was used for estimation of cardiac output by means of first-pass radionuclide angiography performed in the anterior projection. Region of interests (ROIs) were assigned over right ventricle, left ventricle and whole chest, and time activity curves (TACs) were obtained. Cardiac output indices (COIs) were calculated by the following equation; COI = p3/2・Qc/∫t0A(s)ds, where p = number of pixels of the ventricular ROI, Qc = the peak count rate of the TAC obtained from the whole chest's ROI and ∫t0A(s)ds = the area under ventricular TAC. The COI (y) determined by ROI over the left ventricle yield the best correlation with the cardiac output by conventional radionuclide method (x) (y = 0.0381x + 6.22, r = 0.828, n = 48, p < 0.001). In conclusion, cardiac output can be easily measured with first pass data using myocardial perfusion imaging agent.
PracticeClinical medicine
KeywordsCardiac output, Radionuclide, First-pass study, Cardiac output index, Tetrofosmin

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