| Japanese |
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| Title | 原発性肺癌における99mTc - MIBIと201Tl - chlorideの原発腫瘍描出能の比較検討 |
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| Subtitle | 原著 |
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| Authors | 山本由佳*, 川崎幸子***, 西山佳宏*, 福永浩太郎*, 佐藤功*, 高島均*, 大川元臣*, 熊澤良彦****, 藤田次郎**, 田邉正忠* |
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| Authors(kana) | |
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| Organization | *香川医科大学放射線科, **第一内科, ***麻田総合病院放射線科, ****島津製作所医用機器事業部 |
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| Journal | 核医学 |
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| Volume | 33 |
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| Number | 5 |
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| Page | 501-511 |
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| Year/Month | 1996/5 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」原発性肺癌42例に, 99mTc-MIBIと201Tlによる原発腫瘍描出能を比較検討した. 腫瘍(T)と健側肺(N)にROIを設定しT/N ratioを早期像, 後期像より求め, それぞれearly ratio, delayed ratioとし, さらにretention indexを算出した. 201Tlのearly ratio 3.3±1.2, delayed ratio 3.6±1.5, 99mTc-MIBIのearly ratio 2.5±1.1, delayed ratio 2.2±1.0で201Tlは99mTc-MIBIに比べearly, delayed ratioともに高集積であった. retention indexは, 201Tlが12.4±30.9, 99mTc-MIBIが-11.4±18.6で, 201Tlはretentionするものが多く, 逆に99mTc-MIBIはwashoutするものが多かった. 組織別検討ではT/N ratio, retention indexともに, 組織間で有意差は認められなかった. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-MIBI, 201Tl-chloride, Dual radionuclide, SPECT, Lung cancer. |
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| English |
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| Title | Comparative Evaluation of 99mTc - MIBI (hexakis2 - methoxy isobutyl isonitrile) and 201Tl - chloride in Primary Lung Cancer |
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| Subtitle | Original Articles |
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| Authors | Yuka YAMAMOTO*, Yukiko KAWASAKI***, Yoshihiro NISHIYAMA*, Koutarou FUKUNAGA*, Katashi SATOH*, Hitoshi TAKASHIMA*, Motoomi OHKAWA*, Yoshihiko KUMAZAWA****, Jiro FUJITA**, Masatada TANABE* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **First Department of Internal Medicine, Kagawa Medical School, ***Department of Radiology, Asada General Hospital, ****Medical System Division, Shimadzu Corporation |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 33 |
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| Number | 5 |
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| Page | 501-511 |
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| Year/Month | 1996/5 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]We performed comparative study, using 99mTc-MIBI and 201Tl-chloride in patients with primary lung cancer. There were 42 patients with primary lung cancer. All patients underwent dual radionuclide imaging with 201Tl-chloride and 99mTc-MIBI. Regions of interest were placed over the tumor area(T)and contralateral normal lung area(N). A tumor to normal lung ratio(T/N ratio)and retention index were calculated by early and delayed ratios. In the SPECT images, the positive rate was 98% in both the early and delayed images for 201Tl-chloride and 95% in the early and 88% in the delayed images for 99mTc-MIBI. Both early and delayed T/N ratios of 201Tl-chloride were significantly higher than those of 99mTc-MIBI. The retention index of 201Tl-chloride was higher than that of 99Tc-MIBI. T/N ratio and retention index did not significantly correlated with reference to histological types. We conclude that 99mTc-MIBI SPECT can be helpful in localizing Primary lung cancers. However, in our Study the tumor accumulation of 99mTc-MIBI was significantly lower compared with 201Tl-chloride. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-MIBI, 201Tl-chloride, Dual radionuclide, SPECT, Lung cancer. |
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