| Japanese |
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| Title | 99mTc-HMPAO SPECTにおける2回静注法の基礎的検討と負荷試験への応用 |
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| Subtitle | 原著 |
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| Authors | 樋口健史*, 小田野行男*, 高橋直也*, 酒井邦夫* |
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| Organization | *新潟大学医学部放射線医学教室 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 3 |
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| Page | 235-240 |
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| Year/Month | 1995/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」99mTc-HMPAO 2回静注法による負荷試験の評価をより正確に行うため, 安静時背臥位の状態で99mTc-HMPAO 555 MBq (15mCi) を2回連続で静注, おのおのの脳血流SPECTを撮像し, 両画像のカウントの相関を検討した. 6症例150部位で比較した結果, 1st scanの局所のカウントをC1, 2nd scanのそれをC2とするとC2=1.66×C1+106 (1) 式 (r=0.97) を得た. この式はC1の値にかかわらず認められた. 式(1)は同じ条件で撮像した場合の2回目のカウントを1回の撮像で類推できることを示しており, これを負荷試験に応用したところサブトラクション法を用いずに負荷前後の脳血流の変化を評価でき, 臨床応用可能と判断した. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-HMPAO, SPECT, Stress scintigraphy, Cerebral blood flow |
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| English |
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| Title | A Fundamental Study for 99mTc-HMPAO Double Injection Method and Clinical Application to Stress Scintigraphy for Orthostatic Hypotension |
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| Authors | Takeshi HIGUCHI, Ikuo ODANO, Naoya TAKAHASHI, Kunio SAKAI |
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| Organization | Department of Radiology, Niigata University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 3 |
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| Page | 235-240 |
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| Year/Month | 1995/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Double injection method using brain perfusion 99mTc-HMPAO SPECT is popular one for evaluating stress scintigraphy. For appropriate evaluation of this method 555 MBq (15mCi) of 99mTc-HMPAO was injected twice in sequence at the resting state. The first and second SPECT images were obtained 5 min after each injection. Twenty-five ROIs of 8×8 pixels were placed on in various regions of the first images, and calculate each counts (C1). Then the counts of the same region of the second scan were calculated (C2). One hundred and fifty ROIs/6 patients were examined. We derived the linear relationship as C2=1.66×C1+106 (r=0.97), where C1 and C2 represents counts of the first scan, and second scan, respectively. This results suggests that the counts of the second scan is derived from the counts of the first scan without second scanning if they are obtained in the same condition. When we applied this method to stress scintigraphy, it may be useful for evaluating the regional brain perfusion changes before and after loading instead of using subtraction technique. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-HMPAO, SPECT, Stress scintigraphy, Cerebral blood flow |
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