| Japanese |
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| Title | 副甲状腺疾患の診断における塩化タリウム (201Tl) 注射液の有用性 |
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| Subtitle | 《技術報告》 |
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| Authors | 福地稔*, 末廣美津子*, 日下部きよ子**, 牧正子**, 大塚信昭***, 片桐誠****, 鳥塚莞爾***** |
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| Authors(kana) | |
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| Organization | *兵庫医科大学核医学科, **東京女子医科大学放射線科, ***川崎医科大学核医学科, ****川崎医科大学甲状腺外科, *****福井医科大学 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 12 |
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| Page | 1481-1490 |
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| Year/Month | 1993/12 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 臨床的に原発性副甲状腺機能亢進症と診断された18例, 二次性副甲状腺機能亢進症と診断された32例の合計50例(男性31例, 女性19例, 年齢28〜73歳・平均51.5±11.1歳)を対象に塩化タリウム(201Tl)注射液による副甲状腺シンチグラフィを施行し, その臨床診断における有用性について検討した. 手術所見のある34例中28例において201Tlによる画像評価から過機能副甲状腺腫の局在部位が確認でき, うち2例では異所性副甲状腺腫, 1例では副甲状腺癌の旁気管リンパ節への転移の検出が可能であった. 201Tl画像の診断能は, 検出率63.8%, 特異度85.7%, 正診率70.6%であった. 重量別での検出率は1g以上で100%, 0.5g以上1g未満で62.0%, 05g未満で41.5%であった. 201Tl画像による過機能副甲状腺腫の局在診断は, 安全性が高く, 術前に局在部位を確認する検査法としてきわめて有用であった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thallium-201, Parathyroid gland, Hyperparathyroidism. |
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| English |
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| Title | Clinical Utility of Thallium-201 Chloride in the Diagnosis of Parathyroid Glands in Patients with Hyperparathyroidism |
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| Subtitle | Technical Reports |
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| Authors | Minoru FUKUCHI*, Mitsuko SUEHIRO*, Kiyoko KUSAKABE**, Masako MAKI**, Nobuaki OHTSUKA***, Makoto KATAGIRI****, Kanji TORIZUKA***** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine, Hyogo College of Medicine, **Department of Radiology, Tokyo Women's Medical College, ***Department of Nuclear Medicine, Kawasaki Medical School, ****Department of Surgery, Kawasaki Medical School, *****President, Fukui Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 12 |
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| Page | 1481-1490 |
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| Year/Month | 1993/12 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Clinical utility for detection of hyperfunctioning parathyroid glands in patients with primary and secondary hyperparathyroidism (PHPT, SHPT) using 201TlCl and 99mTcO4- images was estimated in 50 patients including 18 PHPT and 32 SHPT (male ; n=31, female ; n=19, 51.5+-11.1 yr). Detection of 94 hyperfunctioning parathyroid glands in 34 cases were achieved correctly by 201TlCl and 99mTcO4- images in agreement with surgical findings. Detectability of hyperfunctioning parathyroid glands was 100% in more than 1.0 g, 62.0% in more than 0.5 g and 41.5% in less than 0.5 g respectively. Ectopic parathyroid glands in two cases and a metastasis to pretracheal lymph node in one case were clearly demonstrated. Our results show that parathyroid scintigraphy using 201TlCl and 99mTcO4- as well as 131I or 123I is useful and safe method for preoperative detection of hyperfunctioning parathyroid glands. |
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| Practice | Clinical medicine |
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| Keywords | Thallium-201, Parathyroid gland, Hyperparathyroidism. |
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