| Japanese |
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| Title | 糖尿病性神経障害における123I-MIBG心筋シンチグラフィの有用性 |
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| Subtitle | 短報 |
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| Authors | 上遠野栄一*, 大和田憲司*, 武田寛人*, 鉄地川原正顕*, 渡辺直彦**, 丸山幸夫** |
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| Authors(kana) | |
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| Organization | *太田西ノ内病院循環器科, **福島県立医科大学第一内科 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 10 |
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| Page | 1235-1239 |
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| Year/Month | 1993/10 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 自律神経障害を伴う糖尿病患者では, 123I-Metaiodobenzylguanidine (123I-MIBG) の心臓への集積が低下する可能性が示唆されている. 今回われわれは, 冠動脈造影を施行された10例の糖尿病患者を糖尿病性triopathyの合併のない6例と合併する4例の2群にわけ, 201Tlと123I-MIBG心筋シンチグラフィを施行し, 両群間の差異を検討した. 123I-MIBG心筋シンチグラフィでは, 糖尿病性triopathy合併群は4例全例が初期像, 後期像とも心尖および下壁に欠損像を示した. triopathy非合併群では6例中4例に異常所見を認めなかったが, 残り2例では心尖および下壁にrapid clearanceの所見を認めた. これら10例とも201Tl心筋像は正常で, 右冠動脈には有意狭窄を認めなかった. 以上より, 糖尿病における交感神経機能障害は, 心尖および下壁によりきたしやすく, triopathyの高度な例でより顕著である可能性が示唆され, 123I-MIBGは糖尿病の心臓交感神経障害の評価に有用であると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-MIBG, Diabetes mellitus, Autonomic neuropathy. |
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| English |
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| Title | Usefulness of Myocardial Imaging by 123I-MIBG in Assessment of Diabetic Neuropathy |
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| Subtitle | Short Communication |
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| Authors | Eiichi KATONO*, Kenji OWADA*, Hiroto TAKEDA*, Masa-aki TECHIGAWARA*, Naohiko WATANABE**, Yukio MARUYAMA** |
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| Authors(kana) | |
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| Organization | *Department of Cardiology, Ohta Nishinouchi Hospital, **First Department of Internal Medicine, Fukushima Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 10 |
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| Page | 1235-1239 |
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| Year/Month | 1993/10 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] In diabetic patients with autonomic neuropathy, it is suggested that there is a reduced uptake of 123I-MIBG in the heart. We compared the difference of myocardial 123I-MIBG accumulation between 4 diabetic patients with triopathy and 6 patients without it. In all 10 patients, coronary angiography and 201Tl imaging (rest and 4 hours later) were performed. 123I-MIBG (111 MBq) was administered intravenously and its imaging was recorded on 15 minutes and 4 hours after injection. In all 4 cases with triopathy, 123I-MIBG imaging showed defect in apical and inferior region. In 2 out of 6 cases without triopathy, rapid clearance was noticed in apical and inferior region. There was no significant stenosis in right coronary artery and no defect in initial and delayed 201Tl images in all cases. We concluded that diabetic autonomic neuropathy in the heart was prominent in apical and inferior region and 123I-MIBG imaging might be useful for the evaluation of degrees in diabetic neuropathy. |
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| Practice | Clinical medicine |
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| Keywords | 123I-MIBG, Diabetes mellitus, Autonomic neuropathy. |
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