| Japanese |
|---|
| Title | 99mTc-tetrofosmin同日2回投与法における検査プロトコールの検討 |
|---|
| Subtitle | 原著 |
|---|
| Authors | 橋本順*, 久保敦司*, 中村佳代子*, 三宮敏和*, 岩永史郎**, 宇野恵子**, 西村洋**, 高橋栄一**, 三田村秀雄**, 半田俊之介**, 小川聡** |
|---|
| Authors(kana) | |
|---|
| Organization | *慶應義塾大学医学部放射線科, **呼吸循環器内科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 30 |
|---|
| Number | 10 |
|---|
| Page | 1191-1201 |
|---|
| Year/Month | 1993/10 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」 99mTc-tetrofosminを同日に2回投与して心筋血流シンチグラフィ負荷・安静時検査を施行する際に, 初回に投与されたRIの残存が2回目の検査に及ぼす影響を考慮し, 検査プロトコールについて検討した. 8例で負荷時検査を, 7例では安静時検査を先行し, 検査間隔は3時間, 投与量は1回目が370MBq, 2回目を740MBqとした. 初回検査時の放射能, 検査間隔, 別に算出した放射能の消失率より2回目の検査時点での初回投与のRI残存による放射能を推定したところ, 2回目検査時のカウントの20-25%程度が初回投与の残存放射能であった. 負荷時検査先行の場合では著明な虚血例で, 安静時検査先行の場合では軽度虚血例で初回投与のRI残存の影響を無視できなかった. 同日投与では検査間隔をよりあけるか, 前後の投与量にさらに差をつける方法が望ましいと考えられた. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | 99mTc-tetrofosmin, SPECT, Same day protocol. |
|---|
| English |
|---|
| Title | Rest and Stress Myocardial Perfusion Imaging on the Same Day with Two Injections of 99mTc-tetrofosmin |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Jun HASHIMOTO*, Atsushi KUBO*, Kayoko NAKAMURA*, Toshikazu SAMMIYA*, Shiro IWANAGA**, Keiko UNO**, Hiroshi NISHIMURA**, Eiichi TAKAHASHI**, Hideo MITAMURA**, Shunnosuke HANDA**, Satoshi OGAWA** |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology, **Department of Internal Medicine, Sehool of Medicine, Keio University |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 30 |
|---|
| Number | 10 |
|---|
| Page | 1191-1201 |
|---|
| Year/Month | 1993/10 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] 99mTc-tetrofosmin myocardial perfusion imagings under different protocols were performed at rest and stress on the same day. In the stress/rest protocol, the exercise study was carried out first, and then the rest one followed. Eight patients were involved in the stress/rest protocol. Seven patients were examined in the reverse, rest/stress protocol. In any protocols, the injection interval was 3 hours, and injection doses in the first and second studies were 370 MBq and 740 MBq, respectively. Myocardial counts were obtained by placing region of interest over the myocardial walls in short axial SPECT images. Based on myocardial counts from the first injection and the wash-out rate of tetrofosmin, we calculated, at the second imaging, counts caused from the first injection. Approximately 20-25% of counts in the second study were found to be caused from the residual radiotracer. The residual radiotracers affected the interpretation of imagings of two patients we examined:one with marked reversible ischemia examined in the stress/rest protocol and the other with mild ischemic change examined in the rest/stress one. Our results suggested that some modifications of studies, such as the increase in the injection intervals or the reduce of the first-to-second dose ratio, might be necessary to conduct the same day protocols. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | 99mTc-tetrofosmin, SPECT, Same day protocol. |
|---|