| Japanese |
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| Title | In-111標識血小板寿命測定における血小板法と全血法の比較検討 |
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| Subtitle | 原著 |
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| Authors | 斉藤京子*, 村田啓**, 塚田理康*** |
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| Organization | *虎の門病院放射線部, **放射線科, ***血液学科 |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 8 |
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| Page | 767-773 |
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| Year/Month | 1988/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」In-111トロポロンを用いた血小板寿命測定において, 血小板分離操作が必要な血小板法, 全血放射能をそのまま血小板の放射能とした補正なし全血法, 血漿中In-111放射能を全血放射能から差し引いた補正全血法, の3法による血小板平均寿命の値を各症例において比較検討した. 荷重平均法により求めた3法の平均寿命が, 8日以上を寿命正常群, 4〜7日を軽度短縮群, 4日以下を著明短縮群とした. 寿命正常群または軽度短縮群において, 血小板法による平均寿命は測定値のバラツキにより, 他法に比べ短めに算出される症例があった. これらの症例を除いた場合, およびバラついた測定点を除いて平均寿命を算出した場合には, 3群において血小板法, 補正なし全血法, 補正全血法の3法による平均寿命に有意差を認めなかった. In-111標識時, 赤血球等の混入が少なければ, 操作性や測定値の信頼性から全血法, 特に補正なし全血法が優れていると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | In-111 tropolone, Platelet survival, Weighted mean, Platelet methcd, Whole blood method. |
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| English |
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| Title | Platelet Weighted Mean Survival Time Estimated by Platelet and Whole Blood Method |
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| Subtitle | - Original Articles - |
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| Authors | Kyoko SAITO*, Hajime MURATA*, Toshiyasu TSUKADA** |
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| Authors(kana) | |
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| Organization | *Divisin of Nuclear Medicine, Toranomon Hospital, **Division of Hematologic Research, Toranomon Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 8 |
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| Page | 767-773 |
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| Year/Month | 1988/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | Weighted mean survival time was estimated by platelet method (P-M), plasma radioactivity corrected whole blood method (CWB-M) and non-corrected whole blood method (NWB-M). Platelets were labeled with In-111 tropolone. In normal platelet survival group, mean survival time by P-M, CWB-M and NWB-M were 8.68+-0.43 (mean+-1SD), 8.80+-0.37 and 8.94+-0.39, respectivety. In short survival group, no significant difference in weighted mean survival time was observed among three methods. In some cases, weighted mean survival time by platelet method was shorter than those by whole blood methods due to the scattering of platelet radioactivity caused by handling of the platelets and/or platelet counting. In the case with smaller erythrocytes contamination during In-111 labeling, the whole blood method especially non-corrected one was useful because it enables easy and precise measurement. |
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| Practice | Clinical medicine |
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| Keywords | In-111 tropolone, Platelet survival, Weighted mean, Platelet methcd, Whole blood method. |
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