| Japanese |
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| Title | 分化型甲状腺癌の転移の検出における201Tl-chlorideシンチグラフィおよびNa 131Iシンチグラフィの意義 |
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| Subtitle | 原著 |
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| Authors | 日下部きよ子*, 井上豊*, 川崎幸子*, 牧正子*, 奈良成子*, 近藤千里*, 西岡隆文*, 広江道昭*, 重田帝子*, 栗原重子**, 出村博**, 小原孝男***, 藤本吉秀***, 山崎統四郎**** |
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| Authors(kana) | |
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| Organization | *東京女子医大放射線科, **東京女子医大ラジオアッセイ科, ***東京女子医大内分泌外科, ****放射線医学研究所臨床研究部 |
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| Journal | 核医学 |
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| Volume | 21 |
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| Number | 8 |
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| Page | 941-951 |
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| Year/Month | 1984/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」分化型甲状腺癌の転移の診断における201Tl-chlorideおよびNa 131Iによるシンチグラフィの価値を比較検討した. 対象66例はいずれも分化型甲状腺癌の診断のもとに甲状腺全摘術が施行され, さらに甲状腺機能低下時のNa 131Iによるシンチグラフィ, 血清サイログロブリン測定のほか, 手術, 剖検などにより転移の診断のなされた症例である. 201Tl-chlorideシンチグラフィのSensitivityは72%, Accuracyは79%で, 陽性率は病理組織型とは相関せず, 転移巣の大きさに相関した. (p<0.005) 131IシンチグラフィのSensitivityは72%で, 病理組織別にみると濾胞腺癌で89%と乳頭腺癌の50%に比し, 有意に高かった. (p<0.005) 201Tlシンチグラフィによる甲状腺癌の転移巣の検索は, 131Iシンチグラフィを補う秀れた診断法であることが確認された. |
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| Practice | 臨床医学：一般 |
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| Keywords | 201Tl-chlorice, 131I, Differentiated thyroid carcinoma, Tumor scintigraphy. |
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| English |
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| Title | Usefulness of Tl-201 Chloride and NaI-131 Scintigraphy in Detection of Metastasis from Thyroid Carcinoma |
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| Subtitle | Original Articles |
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| Authors | Kiyoko KUSAKABE*, Yutaka INOUE*, Yukiko KAWASAKI*, Masako MAKI*, Shigeko NARA*, Chisato KONDO*, Takafumi NISHIOKA*, Michiaki HIROE*, Akiko SHIGETA*, Shigeko KURIHARA**, Hiroshi DEMURA**, Takao OBARA***, Yoshihide FUJIMOTO***, Toshio YAMASAKI**** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Radioassay, ***Surgery, Tokyo Womens Medical College, ****Division of Clinical Research, NIRS |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 21 |
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| Number | 8 |
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| Page | 941-951 |
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| Year/Month | 1984/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]The aim of this study is to compare the Tl-201 scan with I-131 scan and to asses whether Tl-201 scan have diagnostic advantages in the diagnosis and follow-up of patients with thyroid carcinoma. All patients had recieved total thyroidectomy surgically with or without ablation with radioiodine and fifty seven of sixty six patients have measured serum thyroglobulin levels. Tl-201 chloride was given in a dose of 2-4 mCi; patients were scanned after 5 minutes. I-131 imaging was performed 1-7 days after oral administration of 5 or 100 mCi of I-131. The study population included 25 men and 41 women, with ages ranging from 16-75 years. Thirty eight had follicular carcinomas, twenty seven had papillary carcinomas (including mixed papillary-follicular) and one had these two types of carcinomas. A positive Tl-201 scan was obtained in thirty six of fifty patients with metastasis. The sensitivity of Tl-201 scintigraphy was 72%, which was correlated with size of metastatic tumors (p<0.005), and accuracy was 79%. No difference in Tl-201 uptake could be demonstrated between papillary and follicular tumors. The sensitivity of I-131 scan was 72%, which was correlated with histological type (89% of follicular type and 50% of papillary type), and accuracy was 79%. These results indicate that Tl-201 scans have the added advantage of detecting metastasis from thyroid carcinoma including non-functioning metastasis from thyroid carcinoma including non-functioning metastasis. Based on our study, the two methods complement each other to achieve maximum sensitivity and relaiability. |
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| Practice | Clinical medicine |
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| Keywords | 201Tl-chlorice, 131I, Differentiated thyroid carcinoma, Tumor scintigraphy. |
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