| Japanese |
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| Title | 悪性黒色腫における67Ga-citrate腫瘍シンチグラフィの臨床的検討 |
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| Subtitle | 原著 |
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| Authors | 小須田茂*, 高木八重子**, 久保敦司**, 三宮敏和**, 岡野義幸**, 橋本省三**, 西川武二*** |
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| Authors(kana) | |
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| Organization | *国立大蔵病院放射線科, **慶応義塾大学医学部放射線医学教室, ***皮膚科学教室 |
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| Journal | 核医学 |
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| Volume | 21 |
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| Number | 7 |
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| Page | 781-790 |
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| Year/Month | 1984/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」悪性黒色腫における67Ga-citrateによる腫瘍シンチグラフィの臨床的有用性をretrospectiveに評価した. 1)悪性黒色腫患者22例, 63スキャンについて, 病巣有無の検出能はsensitivity 85.7%, specificity 100%, accuracy 95.2%であった. 2)92病巣に対するsensitivityは70.7%, 検出しえた最小病巣は長径4mmの結節性皮膚転移巣であった. 3)術後, ガリウムシンチグラフィを施行した患者のうち, 陽性像を示した患者の予後は陰性像を示した患者のそれに比し, きわめて不良であった. 4)ガリウムシンチグラム上, 陽性像を示した患者の臨床的特徴として, 血液生化学上, 赤沈, CRPの亢進, LDH高値, α2-グロブリン分画の増加があげられた. 以上, ガリウムシンチグラフィは悪性黒色腫患者における術前の転移巣の把握, 治療後の経過観察にきわめて有用な検査法の一つと思われる. |
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| Practice | 臨床医学：一般 |
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| Keywords | Melanoma, 67Ga-citrate scintigraphy. |
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| English |
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| Title | Clinical Assessment of 67Ga-citrate Tumor Scintigraphy in Malignant Melanoma |
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| Subtitle | Original Articles |
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| Authors | Shigeru KOSUDA*, Yaeko TAKAGI**, Atsushi KUBO**, Toshikazu SANMIYA**, Yoshiyuki OKANO**, Shozo HASHIMOTO**, Takeji NISHIKAWA*** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Ohkura National Hospital, **Department of Radiology, ***Department of Dermatology, Keio University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 21 |
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| Number | 7 |
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| Page | 781-790 |
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| Year/Month | 1984/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]In a retrospective study of the value of 67Ga-citrate scan in cases of malignant melanoma, 63 scans were obtained from 22 patients. The overall sensitivity, specificity and accuracy of the 67Ga-citrate scan for detection of affected patients were excellent, that is, 85.7%, 100%, 95.2%, respectively. Of the 92 lesions of grossly or pathologically proven melanoma, 65 (70.7%) were detected by routine 67Ga-citrate scan. The smallest lesion that could be detected was the nodular skin metastasis of 4 mm in diameter. Many patients with positive 67Ga-citrate scan showed elevations of erythrocyte sedimentation rate, C-reactive protain, lactic dehydrogenase and increased levels of alpha-2 globulin in serum total protain. The life expectancy of patients with an abnormal scan was shorter than that of patients with a normal scan. 67Ga-citrate whole body scan reliably revealed the extent of malignant melanoma, and is of value in clinical management. |
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| Practice | Clinical medicine |
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| Keywords | Melanoma, 67Ga-citrate scintigraphy. |
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