English |
Title | Place of Ga-67 scans to assess relapse in patients with esophageal carcinoma |
Subtitle | Original Articles |
Authors | Makoto KONDO*, Shigeru KOSUDA*, Atsushi KUBO*, Minoru UEMATSU*, Noriko OHIGASHI*, Hidekazu MASAKI**, Shozo HASHIMOTO* |
Authors(kana) | |
Organization | *From the Department of Radiology, Keio University School of Medicine, **Present Address : The Department of Radiology, National Children's Hospital |
Journal | The Japanese Journal of nuclear medicine |
Volume | 19 |
Number | 10 |
Page | 1493-1496 |
Year/Month | 1982/12 |
Article | Original article |
Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
Abstract | [ABSTRACT] This study evaluated the role of Ga-67 scans to detect relapse after curative therapy in patients with esophageal carcinoma. Of 37 patients, 30 died subsequently : 19 patients had histological confirmation of relapse, and the other 11 patients showed strong evidence of relapse on clinical evaluation until death. Of the 30 patients who died, 21 had abnormal Ga-67 scans predicting the presence of relapse. Of 16 patients with negative Ga-67 scans, seven patients were alive without evidence of relapse for more than six months after Ga-67 scanning. Most of the relapses were clinically evident, and survival of the patients who relapsed was short. Effort to detect relapse in earlier stages may increase the number of false positives. Although the machine used for this study was scintiscanner and the number of the patients was relatively small, routine use of Ga-67 scans for following up treated esophageal carcinoma patients may be not cost-effective. |
Practice | Clinical medicine |
Keywords | Radionuclide Scan, Gallium-67 Citrate, Esophageal Carcinoma |
Japanese |
Title | 食道癌の再燃とGa-67スキャンの役割 |
Subtitle | 原著 |
Authors | 近藤誠*, 小須田茂*, 久保敦司*, 植松稔*, 大東紀子*, 正木英一**, 橋本省三* |
Authors(kana) | |
Organization | *慶応義塾大学医学部放射線科, **現国立小児病院放射線科 |
Journal | 核医学 |
Volume | 19 |
Number | 10 |
Page | 1493-1496 |
Year/Month | 1982/12 |
Article | 原著 |
Publisher | 日本核医学会 |
Abstract | 「要旨」 根治治療後の食道癌症例においてGa-67スキャンを施行し, 寄与を調べた. 37例中30例は後に死亡し, 組織学的にもしくは臨床的に死因は食道癌の再燃によると考えられた. 30の死亡例のうち, 21例は再燃部位を示唆するGa-67の異常集積像を示した. Ga-67スキャンで異常の見つからなかった16例中7例はGa-67スキャン後6か月以上再燃の徴なく健存である. 再燃部位のほとんどは他の臨床検査手段によって明らかであり, 再発患者の生存期間は短かい. より早期に再燃を発見しようとする努力は, 無病誤診率をも上昇させるかもしれない. 本研究で使用した機械はシンチスキャナーで, 症例数も限られているが, Ga-67スキャンを食道癌症例の経過観察にルーチンに使用するのは, 費用・効果比から見て有益ではないと思われた. |
Practice | 臨床医学:一般 |
Keywords | Radionuclide Scan, Gallium-67 Citrate, Esophageal Carcinoma |