| Japanese |
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| Title | 75Se-selenomethionineの血中, 膵液, 胆汁中における動態について |
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| Subtitle | 研究速報 |
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| Authors | 中山信一*, 水上忠久*, 森田誠一郎*, 梅崎典良*, 深江俊三*, 大竹久*, 河野彬**, 矢野潔*** |
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| Authors(kana) | |
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| Organization | *久留米大学医学部放射線医学教室, **九州がんセンター研究部, ***福岡県立柳川病院放射線科 |
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| Journal | 核医学 |
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| Volume | 17 |
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| Number | 5 |
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| Page | 579-582 |
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| Year/Month | 1980/6 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」 膵疾患の診断は, 検査技術が進歩した今日でも, 困難なものの一つとされている. 膵の検査法としては多くの方法が検討され, その結果が報告されているが, いずれの方法も, 未だ不十分で未解決な問題が多い. 膵の形態学的診断法の一つである膵シンチグラフィは, 診断に際して十分な情報を与えていないことがしばしば経験される. われわれは膵シンチグラフィに用いられる75Se-selenomethionineの動態を動物実験にて再検討することを試み, 血液, 膵液, 胆汁中のRI動態を検討したところ若干の知見を得たので報告する. 「II. 実験材料および実験方法」 ラット (Wister♂, 8〜10週齢) をエーテル麻酔下に開腹し, 総胆管開口部の反対側腸管を約1cm切開してポリエチレンチューブ (IGARASHI IKA KOGYO No. 5) を総胆管開口部に約2mm挿入固定し, 膵胆汁混合液を採取した. |
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| Practice | 臨床医学：一般 |
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| Keywords | 75Se-selenomethionine, Pancreas scitigraphy, Thin layer chromatography, Autoradiography |
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| English |
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| Title | Dynamic Changes of 75Se-selenomethionine in the Blood, Pancreatic Juice and Bile |
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| Subtitle | Rapid Communications |
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| Authors | Sinichi NAKAYAMA*, Tadahisa MIZUKAMI*, Seiichiro MORITA*, Noriyoshi UMEZAKI*, Shunzo FUKAE*, Hisashi OHTAKE*, Akira KONO**, Kiyoshi YANO*** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Kurume University School of Medicine, **Research Institute, Kyushu Cancer Center, ***Department of Radiology, Yanagawa Public Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 17 |
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| Number | 5 |
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| Page | 579-582 |
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| Year/Month | 1980/6 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] As one of the methods of approach to the diagnosis of pancreatic diseases, dynamics of 75Se-selenomthionine in the blood, pancreatic juice and bile of rats were studied by thin layer chromatography and autoradiography as reported below. Thin layer chromatography followed by autoradiography carried out on samples obtained by various methods revealed accumulation of radioactivity at 5 sites, called A, B, C, D and E according to the ascending order of Rf values, 0.00, 0.13, 0.51, 0.64 and 0.77 respectively. The following results were obtained in each sample. 1. 75Se-selenomethionine of blood accumulated at 2 sites, A and C (Fig. 1) . 2. Radioactivity of pancreatic juice-bile mixture accumulated at 4 sites, A, C, D and E (Fig. 2) . 3. Radioactivity of the bile, as that of the pancreatic juice-bile mixture, accumulated at A, C, D and E, but only a very small amount accumulated in A (Fig. 3) . 4. Radioactivity in the pancreatic juice accumulated at 2 sites, A and C, and a very large amount was found in A (Fig. 4) . 5. The original solution of 75Se-selenomethionine used as the control revealed accumulation of radioactivity at A, B and C (Fig. 1, 2, 3, 4) . |
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| Practice | Clinical medicine |
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| Keywords | 75Se-selenomethionine, Pancreas scitigraphy, Thin layer chromatography, Autoradiography |
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