| Japanese |
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| Title | 81mKrガスによる肺機能検査の診断的意義 - 99mTc-MAAによる肺血流検査とmismatchを示した症例を中心に - |
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| Subtitle | 原著 |
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| Authors | 楢林勇*, 伊藤安彦*, 大塚信昭*, 村中明*, 横林常夫*, 寺島秀彰* |
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| Organization | *川崎医科大学放射線科核医学教室 |
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| Journal | 核医学 |
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| Volume | 16 |
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| Number | 3 |
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| Page | 309-319 |
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| Year/Month | 1979/5 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」43例の各種肺疾患症例を対象として, 81mKrガスの連続吸入による肺換気分布を検討した. 81mKrは物理的半減期が著しく短かく, wash-out曲線の作成やgas trappingの描画には適さないが, 大量投与が可能であり, 190keVのγ線はイメージングに適しており, 鮮明な画像を描出し得た. 37例については, 99mTc-MAAによる肺血流分布と対比し, mismatch症例を中心に考察した. 肺血管異常では, 肺換気・血流検査とともに99mTc-HSAによるアンギオグラフィーを併用することにより, より多くの病態生理学的情報を知り得た. 肺癌でも容易に肺換気機能を把握することが可能であり, 放射線治療前後の肺機能の比較により回復率を算出し得た. |
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| Practice | 臨床医学：一般 |
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| Keywords | 81mKr gas, 99mTc-MAA, discrepancy between ventilation and perfusion |
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| English |
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| Title | Diagnostic Significance of Lung Ventilation Study with 81mKr Gas : In Reference to the Discrepant Cases between Ventilation and Perfusion |
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| Subtitle | Original Articles |
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| Authors | Isamu NARABAYASHI, Yasuhiko ITO, Nobuaki OHTSUKA, Akira MURANAKA, Tsuneo YOKOBAYASHI, Hideaki TERASHIMA |
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| Organization | Division of Nuclear Medicine, Kawasaki Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 16 |
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| Number | 3 |
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| Page | 309-319 |
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| Year/Month | 1979/5 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Lung ventilation study was performed on 43 patients by the continuous inhalation of 81mKr gas from a 81Rb-81mKr generator (Nihon Mediphysics Inc. Hyogo Japan) . The patients were measured in a sitting position using a scintillation camera in conjunction with a data processor. In 37 cases, scintigraphic findings were compared with those of 99mTc-MAA images. We discussed the ventilation/perfusion mismatching cases, especially in those of the pulmonary arterial abnormarity and lung cancer. In some of the discrepancy between ventilation and perfusion, nuclear angiography with 99mTc-HSA was performed. The following results were obtained by those studies. 1) The distribution of 81mKr gas within the lung is considered proportional to regional ventilation because of a short half life of 81mKr (13 seconds) . 2) The ventilation image with 81mKr gas was clearly visualized because of the lower gamma-ray energy and much accumulation of activity. 3) Combined use of ventilation-perfusion scintigraphy and nuclear angiography of ten gave us new additional informations about the pathophysiological condition of lung. 4) In mismatching cases of lung cancer, perfusion was usually more impaired than ventilation. |
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| Practice | Clinical medicine |
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| Keywords | 81mKr gas, 99mTc-MAA, discrepancy between ventilation and perfusion |
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