| Japanese |
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| Title | 心筋梗塞症の急性期および慢性期における201TlCl/123I-BMIPP心筋シンチグラムの乖離現象と局所壁運動および糖代謝の関係 |
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| Subtitle | 原著 |
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| Authors | 田中聡彦* |
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| Authors(kana) | |
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| Organization | *大阪市立大学医学部第一内科 |
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| Journal | 核医学 |
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| Volume | 35 |
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| Number | 9 |
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| Page | 857-869 |
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| Year/Month | 1998/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」心筋梗塞急性期および慢性期において, 201TlCl/123I-BMIPP心筋SPECTに観察される心筋血流と脂肪酸代謝の乖離現象の意義を, 心エコーおよびFDG-PETを用いて検討した. 対象は初回急性心筋梗塞症52例(278領域). 心筋梗塞急性期におけるTl/BMIPP乖離領域(乖離領域)では, 非乖離領域に比してFDGの有意な高集積を認めたが, 慢性期においては両者に有意差を認めなかった. 慢性期に存在するTl/BMIPP乖離領域では, 非乖離領域に比してwall motion scoreが有意に低かった. 急性期乖離領域では, 非乖離領域に比して急性期から慢性期にかけて有意な壁運動の改善が認められた. 慢性期冠動脈造影上有意狭窄の有無により非狭窄例と狭窄例に分類し比較検討すると, 非狭窄例においてTl/BMIPP乖離度は急性期から慢性期にかけて有意な減少を認めたが, 狭窄例においては有意な変化を認めなかった. 以上より, Tl/BMIPP心筋SPECTはその乖離現象の有無を利用することにより, 将来の壁運動改善の予測や慢性期の残存虚血の判定に有用と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Myocardial viability, Myocardial blood flow, Myocardial fatty acid metabolism, Wall motion, FDG-PET. |
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| English |
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| Title | The Relationship between Discrepant Areas on 201TlCl/123I-BMIPP Myocardial Scintigraphy, Local Wall Motion, and Glucose Metabolism in Patients with Myocardial Infarction |
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| Subtitle | Original Articles |
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| Authors | Akihiko TANAKA |
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| Authors(kana) | |
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| Organization | First Department of Internal Medicine, Osaka City University Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 35 |
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| Number | 9 |
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| Page | 857-869 |
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| Year/Month | 1998/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | In order to clarify the significance of the discrepancy between myocardial blood flow and fatty acid metabolism on 201TlCl/123I-BMIPP SPECT after acute myocardial infarction, we examined 52 patients (278 segments) with their first acute myocardial infarction using two-dimensional echocardiography and FDG-PET. Patients with T1/BMIPP discrepancy in the acute stage showed higher FDG accumulation than those without Tl/BMIPP discrepancy. In the chronic stage, however, there was no significant difference between both groups. Patients with Tl/BMIPP discrepancy in the chronic stage had lower wall motion scores than those without Tl/BMIPP discrepancy. Significant improvement of the wall motion score was recognized in patients who showed Tl/BMIPP discrepancy in the acute stage. Patients were classified into stenosis and non-stenosis groups by the presence of significant stenosis on coronary angiography in the chronic stage. In the stenosis group, the Tl/BMIPP discrepancy did not show much change from the acute to chronic stage, but there was a significant decrease in the non-stenosis group. It was concluded that 201TlCl/123I-BMIPP myocardial SPECT is useful for predicting future improvement of wall motion and determining the residual ischemia in the chronic stage based on the presence or absence of this discrepancy. |
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| Practice | Clinical medicine |
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| Keywords | Myocardial viability, Myocardial blood flow, Myocardial fatty acid metabolism, Wall motion, FDG-PET. |
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