| Japanese |
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| Title | 胆道閉鎖症術後症例における99mTc-GSAと99mTc-PMTの肝クリアランスの比較 |
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| Subtitle | 原著 |
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| Authors | 山崎哲郎*, 丸岡伸**, 山田章吾* |
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| Authors(kana) | |
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| Organization | *東北大学医学部放射線医学講座, **東北大学医療短期大学部診療放射線学科 |
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| Journal | 核医学 |
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| Volume | 35 |
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| Number | 9 |
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| Page | 849-856 |
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| Year/Month | 1998/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」胆道閉鎖症に対する99mTc-GSA肝シンチグラフィの有用性についての報告は少なく, 99mTc-PMT肝胆道シンチグラフィとの対比はほとんど行われていない. 両者の意義を検討するため, 胆道閉鎖症術後症例41人に対して行われた56回の99mTc-GSA肝シンチグラフィの機能指標について, 同時期に施行した99mTc-PMT肝胆道シンチグラフィと対比した. 99mTc-GSAの肝クリアランスと99mTc-PMTの肝クリアランスとの間には相関を認めたが, 一部の症例では黄疸の影響と考えられる乖離を認めた. 99mTc-GSA肝シンチグラフィは, 黄疸の影響を受けることなく胆道閉鎖症術後症例の肝予備能を正確に評価する方法として有用であり, また99mTc-PMT肝胆道シンチグラフィの併用は, 胆道閉鎖症術後症例における肝障害発生のプロセスの把握に役立つと考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Biliary atresia, Asialoglycoprotein receptor imaging, Hepatobiliary scintigraphy, Liver function. |
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| English |
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| Title | Hepatic Clearance of 99mTc-GSA in Cases of Postoperative Biliary Atresia - A Retrospective Comparison with Hepatic Clearance of 99mTc-PMT - |
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| Subtitle | Original Articles |
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| Authors | Tetsuro YAMAZAKI*, Shin MARUOKA**, Shogo YAMADA* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Tohoku University, School of Medicine, **Department of Radiological Technology, College of Medical Science, Tohoku University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 35 |
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| Number | 9 |
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| Page | 849-856 |
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| Year/Month | 1998/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | There are a few reports about usefulness of 99mTc-GSA liver scintigraphy (GSA imaging) for the evaluation of postoperative state of biliary atresia. However, comparison of significance for the disease between GSA imaging and 99mTc-PMT hepatobiliary imaging have not been reported. Fifty-six GSA imagings for 41 postoperative biliary atresia patients were reviewed and their scintigraphic findings and the functional parameters were compared with those obtained from 99mTc-PMT hepatobiliary imaging. In quantitative analysis, although the hepatic clearance of both tracers calculated by graphical analysis (Patlak plot) were well correlated in most cases, a discrepancy was observed in several cases with jaundice. The authors conclude that the hepatic clearance of 99mTc-GSA is a more accurate index of the hepatic reserve than that of 99mTc-PMT which can be influenced by hyperbilirubinemia and that the combination of both examinations is helpful to evaluate development of liver injury in postoperative biliary atresia patients. |
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| Practice | Clinical medicine |
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| Keywords | Biliary atresia, Asialoglycoprotein receptor imaging, Hepatobiliary scintigraphy, Liver function. |
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