| Japanese |
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| Title | 狭心症の病態からみた123I-BMIPP集積低下の意義 |
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| Subtitle | 原著 |
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| Authors | 黒澤和彦*, 上遠野栄一**, 大和田憲司**, 大谷弘*, 斎藤富善*, 丸山幸夫* |
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| Organization | *福島県立医科大学第一内科, **太田西ノ内病院循環器科 |
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| Journal | 核医学 |
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| Volume | 35 |
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| Number | 5 |
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| Page | 265-272 |
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| Year/Month | 1998/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」虚血性心疾患においてTl心筋シンチの集積がほとんど障害されていないのにもかかわらずBMIPPの集積低下をきたす症例がある. その病態を臨床的に検討するために安定労作性狭心症(n=10)および不安定狭心症(n=16)の26例を対象とした. 安静時201Tlと123I-BMIPPの dual SPECT を行い, 同一平面の画像を視覚的に評価し, 臨床経過, 心電図, 左室造影上の壁運動と比較した. BMIPP集積低下は11例, 正常は15例で認められた. 両群では発作の持続時間と有病期間に差はなかったが, 心電図変化(陰性T波やq波)例と壁運動異常例にBMIPPの集積低下が多く認められた(p<0.001). 血行再建術後の経過を追跡できた症例(n=18)では壁運動低下のみられた16例中12例で改善を認めた. Tl心筋シンチが正常でも, BMIPPの集積低下は高度の心筋虚血を反映すると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-BMIPP, 201TlCl, Myocardial SPECT, Ischemic heart disease, Unstable angina pectoris |
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| English |
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| Title | The Significance of 123I-BMIPP Myocardial SPECT on the Evaluation of Angina Pectoris |
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| Subtitle | Original Articles |
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| Authors | Kazuhiko KUROSAWA*, Eiichi KATOHNO**, Kenji OHWADA**, Hiroshi OHTANI*, Tomiyoshi SAITOU*, Yukio MARUYAMA* |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, Fukushima Medical College, **Department of Cardiovascular Division, Ohta Nishinouchi Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 35 |
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| Number | 5 |
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| Page | 265-272 |
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| Year/Month | 1998/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | Some patients of ischemic heart disease have low uptake in 123I-labeled beta methyl-iodophenyl pentadecanoic acid (BMIPP) SPECT in spite of normal uptake in thallium-201 (Tl) SPECT. To investigate their clinical significance, we performed both Tl and BMIPP myocardial SPECT in 26 cases with stable angina (n = 16) and unstable angina (n = 10), and compared with clinical backgrounds electrocardiogram (ECG) and left ventriculography (LVG). In 11 patients of them, the uptake of BMIPP was moderately reduced. We divided 26 cases into two groups according to uptake of BMIPP (normal/reduced). The two groups had no differences in length of angina attack and duration of disease, but they had a significant difference in the abnormality of either ECG or LVG. Three to six months after PTCA, we examined LVG in 18 cases, 12 of 16 cases with the abnormality of LVG showed the improvement of wall motion. We concluded the reduced uptake of BMIPP with normal uptake of Tl was related to more severe ischemia in cases with unstable angina. |
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| Practice | Clinical medicine |
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| Keywords | 123I-BMIPP, 201TlCl, Myocardial SPECT, Ischemic heart disease, Unstable angina pectoris |
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