| Japanese |
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| Title | 虚血性心疾患における運動負荷99mTc-Tetrofosmin心筋シンチグラフィの肺野集積測定の臨床的意義 |
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| Subtitle | 原著 |
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| Authors | 谷垣光司*, 小林秀樹**, 百瀬満**, 高良綾子***, 金谷信一*, 寺田慎一郎*, 池上晴彦**, 日下部きよ子** |
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| Authors(kana) | |
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| Organization | *東京女子医科大学病院放射線部, **東京女子医科大学放射線科, ***東京女子医科大学循環器内科 |
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| Journal | 核医学 |
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| Volume | 35 |
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| Number | 4 |
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| Page | 189-195 |
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| Year/Month | 1998/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」虚血性心疾患81例を対象に99mTc-Tetrofosmin(TF)運動負荷心筋シンチグラフィを行い, 肺野心筋TF集積比(P/M)を定量し, 多枝病変例の虚血検出ならびに重症度評価への有用性を検討した. 対象例中の21例では, TF運動負荷心筋シンチグラフィと同時期に201TlCl(Tl)運動負荷心筋シンチグラフィを行った. TFとTlとのP/Mの相関はr=0.86と良好であった. 81例全例におけるTFのP/Mと冠動脈造影所見との比較検討では, 3枝病変でP/Mは高値を示したが, 冠動脈狭窄度との有意な関係は見られなかった. TFのP/Mと左室駆出率との比較では, LVEFが50%未満の症例でP/Mが有意に高値を示した. したがって, TFのP/Mの定量は, 虚血の検出精度の向上ならびに心筋虚血の重症度判定に臨床的有用性が確認され, 付加的指標として有用であることが示された. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-Tetrofosmin, 201TlCl, Pulmonary to myocardial uptake ratio, Left ventricular ejection fraction (LVEF), Coronary artery disease (CAD) |
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| English |
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| Title | Clinical Utility of Pulmonary 99mTc-Tetrofosmin Uptake Measurement by the Exercise Myocardial Scintigraphy in Patients with Ischemic Heart Disease |
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| Subtitle | Original Articles |
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| Authors | Koji TANIGAKI*, Hideki KOBAYASHI**, Mitsuru MOMOSE**, Ayako TAKARA***, Shinichi KANAYA*, Shinichiro TERADA*, Haruhiko IKEGAMI**, Kiyoko KUSAKABE** |
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| Authors(kana) | |
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| Organization | *Department of Radiological Service, Tokyo Women's Medical College Hospital, **Department of Radiology, Tokyo Women's Medical College, ***Department of Cardiology, Tokyo Women's Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 35 |
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| Number | 4 |
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| Page | 189-195 |
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| Year/Month | 1998/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | Increased pulmonary 201TlCl (Tl) uptake during exercise has been used as a marker of multivessel critical stenosis. We studied whether pulmonary 99mTc-Tetrofosmin (TF) uptake measurement during exercise is useful as an additional indicator for the detection of coronary artery disease. Pulmonary to myocardial uptake ratio (P/M) measured by TF scintigraphy during exercise were compared with findings of coronary angiography in eighty one patients with ischemic heart disease and also P/M measured with Tl in twenty one cases. TF P/M level in the patients with triple vessel disease was higher than that in the patients with no coronary stenosis, single vessel disease and double vessel disease. However, there was no significant correlation between TF P/M and the severity of coronary artery stenosis. Inverse correlation was observed between TF P/M and left ventricular ejection fraction (LVEF) (r = 0.29, p < 0.01). TF P/M in the patients less than 50% of LVEF was significantly higher than that in the patients over 50% of LVEF (p = 0.05). TF P/M was well correlated with Tl P/M (r = 0.86). In conclusion, quantitative TF P/M during exercise was thought to be useful indicator for the evaluation of coronary artery disease. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-Tetrofosmin, 201TlCl, Pulmonary to myocardial uptake ratio, Left ventricular ejection fraction (LVEF), Coronary artery disease (CAD) |
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