Japanese
Title201Tl-SPECTと13NH3-PETによる心筋血流の比較検討 - 視覚的および定量的評価 -
Subtitle原著
Authors王麗娟*, 河邉讓治*, 重松誠*, 岡村光英*, 小山孝一*, 越智宏暢*, 山岸広幸**, 秋岡要**, 田中聡彦**
Authors(kana)
Organization*大阪市立大学医学部核医学研究室, **大阪市立大学医学部第一内科
Journal核医学
Volume35
Number3
Page131-140
Year/Month1998/3
Article原著
Publisher日本核医学会
Abstract「要旨」非心筋梗塞(non-MI)患者7例および心筋梗塞(MI)患者42例を対象に, 心筋血流について201Tl-SPECTと13NH3-PETを視覚的および定量的に比較検討した. 方法: 201Tl-SPECTおよび13NH3-PET像から視覚的には4段階の欠損スコア(DS)を, 定量的には極座標図を用い % uptake を算出した. 結果: non-MI患者の左室各部位の NH3 % uptake では側壁は中隔に比し有意に低かった. また側壁においては NH3 % uptake は Tl % uptake に比し有意に低かった. MI患者の各部位のDSでは201Tl-SPECTと13NH3-PETとの間に高い一致率が見られた. また前壁中隔梗塞領域では Tl % uptake と NH3 % uptake の比は1に近い値を示し, 両者の間には良好な正の相関が見られた. 下壁梗塞領域ではその比は1より高い値を示したが, 両者にも有意な正の相関が認められた. 総括: 201Tl-SPECTは13NH3-PETと同等に前壁中隔および下壁の心筋血流を評価できるが, 側壁では各々の分布に差異が見られるため, 心筋血流を評価するとき側壁においては注意を要する.
Practice臨床医学:一般
Keywords201Tl-SPECT imaging, 13NH3-PET imaging, Myocardial perfusion, Visual and quantitative evaluation
English
TitleA Comparative Study of Imaging of Myocardial Perfusion with 201Tl-SPECT and 13NH3-PET : Visual and Quantitative Evaluation
SubtitleOriginal Articles
AuthorsLijuan WANG*, Joji KAWABE*, Makoto SHIGEMATSU*, Terue OKAMURA*, Koichi KOYAMA*, Hironobu OCHI*, Hiroyuki YAMAGISHI**, Kaname AKIOKA**, Akihiko TANAKA**
Authors(kana)
Organization*Division of Nuclear Medicine, Osaka City University Medical School, **First Department of Internal Medicine, Osaka City University Medical School
JournalThe Japanese Journal of nuclear medicine
Volume35
Number3
Page131-140
Year/Month1998/3
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractWe compared the results of visual and quantitative evaluation of imaging of myocardial perfusion with 201Tl-SPECT and 13NH3-PET in the 7 non-myocardial infarction (non-MI) and 42 myocardial infarction (MI) patients. On the 201Tl-SPECT and 13NH3-PET imaging, the degree of accumulation of each radioisotope (RI) was visually classified into four grades of defect score. The percentage of uptake was also quantitatively evaluated. Results: In the 7 non-MI patients, NH3 % uptake in the lateral wall was significantly lower than in the septum, and in the lateral wall NH3 % uptake was significantly lower than Tl % uptake. For the 42 MI patients, segmental defect scores (DS) on 201Tl-SPECT were compared with those on 13NH3-PET, and a high degree of concordance in DS was found for all territories of the left ventricle, antero-septum MI and inferior MI territories. Average Tl % uptake/NH3 % uptake was near 1, a highly positive correlation was found between Tl % uptake and NH3 % uptake in all territories of the left ventricle and antero-septum MI territories, and Tl % uptake/NH3 % uptake was lager than 1, but, a significant positive correlation existed between Tl % uptake and NH3 % uptake in the territory with inferior MI. Conclusion: These findings indicate that results of 201Tl-SPECT imaging were similar to those of 13NH3-PET in evaluation of myocardial perfusion in the antero-septum and inferior. However, a difference in distribution was observed between 201TlCl and 13NH3 in the lateral wall, indicating that particular attention should be paid to the results of imaging of myocardial perfusion in the lateral wall.
PracticeClinical medicine
Keywords201Tl-SPECT imaging, 13NH3-PET imaging, Myocardial perfusion, Visual and quantitative evaluation

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