Japanese
Title小児症例の脳血流SPECTにおける散乱・減弱補正の意義
Subtitle原著
Authors足立至*, 土井健司*, 小森剛*, 彭信義*, 田渕耕次郎*, 宇都宮啓太*, 松井律夫*, 末吉公三*, 楢林勇*
Authors(kana)
Organization*大阪医科大学放射線医学教室
Journal核医学
Volume35
Number1
Page1-6
Year/Month1998/1
Article原著
Publisher日本核医学会
Abstract「要旨」小児例の脳血流SPECTでは大脳皮質, 深部灰白質の分別能の低いことが多い. しかし小児例では体動, 鎮静剤の使用等の時間的制約から患児の投影データ収集の延長や被曝を伴う透過型CT(transmission CT)を行うことは困難である. 今回われわれは小児例の脳血流SPECT画像を改善するため triple-energy-window (TEW) 法によるコンプトン散乱の補正および Chang 法による減弱補正を行い, 従来の補正をしない方法と小児31例を対象に対比検討した. その結果, 各種の補正を加えた方法は補正を加えない従来の方法に比べて, 視床, レンズ核等の深部灰白質の描出能が改善し, 定量的にも有意な集積の改善が得られ, かつ病巣部の検出も向上した. 各種補正を加えることはSPECT処理時間が延長するが, 被検者の負担は従来と同じであり, 小児例では望ましい方法と考えられた.
Practice臨床医学：一般
KeywordsBrain perfusion, SPECT, Scatter correction, Attenuation correction
English
TitleClinical Usefulness of Scatter and Attenuation Correction for Brain Single Photon Emission Computed Tomography (SPECT) in Pediatrics
SubtitleOriginal Articles
AuthorsItaru ADACHI, Kenji DOI, Tsuyoshi KOMORI, Nobuyoshi HOU, Koujirou TABUCHI, Ritsuo MATSUI, Kouzou SUEYOSHI, Keita UTSUNOMIYA, Isamu NARABAYASHI
Authors(kana)
OrganizationDepartment of Radiology, Osaka Medical College
JournalThe Japanese Journal of nuclear medicine
Volume35
Number1
Page1-6
Year/Month1998/1
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractThis investigation was undertaken to study clinical usefulness of scatter and attenuation correction (SAC) of brain SPECT in infants to compare the standard reconstruction (STD). The brain SPECT was performed in 31 patients with 19 epilepsy, 5 cerebro-vascular disease, 2 brain tumor, 3 meningitis, 1 hydrocephalus and psychosis (mean age 5.0 +- 4.9 years old). Many patients was necessary to be injected sedatives for restraining body motion after Technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) was injected at the convulsion or rest. Brain SPECT data were acquired with triple detector gamma camera (GCA-9300 Toshiba Japan). These data were reconstructed by filtered backprojection after the raw data were corrected by triple energy windows method of scatter correction and Chang filtered method of attenuation correction. The same data was reconstructed by filtered backprojection without these corrections. Both SAC and STD SPECT images were analyzed by the visual interpretation. The uptake ratio of cerebral basal nuclei was calculated by the counts of the thalamus or lenticular nuclei divided by the cortex. All images of SAC method were excellent than that of STD method. The thalamic uptake ratio in SAC method was higher than that of STD method (1.22 +- 0.09 > 0.87 +- 0.22 p < 0.01). The lenticular nuclear uptake ratio in SAC method was higher than that of STD method (1.26 +- 0.15 > 1.02 +- 0.16 p < 0.01). Transmission scan is the most suitable method of absorption correction. But the transmission scan is not adequate for examination of children, because this scan needs a lot of time and the infants are exposed by the line source radioisotope. It was concluded that these scatter and absorption corrections were most suitable method for brain SPECT in pediatrics.
PracticeClinical medicine
KeywordsBrain perfusion, SPECT, Scatter correction, Attenuation correction

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