| Japanese |
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| Title | 心不全におけるMIBG検査の定量評価に関するアンケート調査 |
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| Subtitle | 総説 |
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| Authors | 西村恒彦*, 杉下靖郎**,†, 佐々木康人***,† |
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| Organization | *大阪大学医学部トレーサ情報解析, **筑波大学臨床医学系内科, ***放射線医学総合研究所, †日本循環器学会・日本核医学会合同心臓核医学に関するワーキンググループ (代表) |
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| Journal | 核医学 |
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| Volume | 34 |
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| Number | 12 |
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| Page | 1139-1148 |
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| Year/Month | 1997/12 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」日本循環器学会と日本核医学会の心臓核医学に関するワーキンググループの共同作業としてMIBG(123I-metaiodobenzylguanidine)の心不全における定量評価に関してアンケート調査を行った. 調査用紙を送付した68施設中49施設(72.1%)から回答が得られた. これらの結果に基づき, 心不全における検査頻度, 撮像法, 定量評価, 検査目的などにつき検討した. 心不全の定量評価において, MIBG心筋シンチグラフィにおける心/上縦隔比(H/M比)および washout rate は臨床的に有用な指標であることが確認された. 今後, 心不全におけるMIBG検査が日常診療に定着することが期待される. 「緒言」心臓核医学に関して, 日本循環器学会と日本核医学会のワーキンググループ(代表: 杉下靖郎 筑波大臨床医学系内科, 佐々木康人 放射線医学総合研究所)が中心となり, 種々の活動が行われている. |
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| Practice | 臨床医学：一般 |
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| Keywords | MIBG, Heart failure, Quantitative analysis |
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| English |
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| Title | The Results of Questionnaire on Quantitative Assessment of 123I-Metaiodobenzylguanidine Myocardial Scintigraphy in Heart Failure |
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| Subtitle | Reviews |
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| Authors | Tsunehiko NISHIMURA*, Yasurou SUGISHITA**, Yasuhito SASAKI*** |
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| Organization | *Department of Tracer Kinetics and Nuclear Medicine, Osaka University, Medical School, **Cardiovascular Division, Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, ***National Institute of Radiological Sciences |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 34 |
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| Number | 12 |
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| Page | 1139-1148 |
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| Year/Month | 1997/12 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | This study was done by working group under the cooperation between Japanese Society of Nuclear Medicine and Japanese Circulation Society. We evaluated the usefulness of quantitative assessment of 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in heart failure by the results of questionnaire. Forty-nine (72.1%) of 68 selected institutions participated in this study. The incidence of MIBG myocardial scintigraphy used in heart failure was 41.1%. The imaging protocol was mostly done by both planar and SPECT at 15 min and 3.6 hr after intravenous injection of 111 MBq of MIBG. The quantitative assessment was mostly done by heart/mediastinum (H/M) ratio and washout rate analysis based on planar imaging. The mean normal value of H/M ratio were 2.34 +- 0.36, and 2.49 +- 0.40, at early and delayed images, respectively. The normal value of washout rate was 27.74 +- 5.34%. On the other hand, those of H/M ratio in heart failure were 1.87 +- 0.27, and 1.75 +- 0.24, at early and delayed images, respectively. That of washout rate was 42.30 +- 6.75%. These parameters were very useful for the evaluation of heart failure. In conclusion, MIBG myocardial scintigraphy was widely used for not only early detection and severity assessment, but also indication for therapy and prognosis evaluation in heart failure patients. |
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| Practice | Clinical medicine |
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| Keywords | MIBG, Heart failure, Quantitative analysis |
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