| Japanese |
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| Title | 123I - MIBG心筋シンチグラムにおけるクリアランス - SPECT法とplanar法の比較 - |
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| Subtitle | 短報 |
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| Authors | 塚本正樹*, 寺田幸治**, 米山聡嗣*, 立川弘孝*, 加藤周司* |
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| Organization | *朝日大学歯学部附属村上記念病院内科, **公立南丹病院内科 |
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| Journal | 核医学 |
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| Volume | 34 |
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| Number | 9 |
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| Page | 827-830 |
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| Year/Month | 1997/9 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」123I-MIBG心筋シンチグラムにおいて心臓からのMIBGのクリアランスは, 心疾患の重症度評価に有用とされている. クリアランスの算出には, SPECT像から算出する方法(S法)とplanar像から算出する方法(p法)がある. 筆者らは健常群10例, 疾病群158例を対象とし, 2法の異常検出率の差異を検討した. MIBG111MBq静注15分後と4時間後に撮像し, それぞれの方法でクリアランスを算出した. 健常群の平均値+標準偏差以上をクリアランス異常亢進とすると, S法のみ異常を示したのが32例, p法のみ異常を示したのが5例で, 異常検出頻度はS法がより高かった. 心不全などでは, 肺からのクリアランスが低下することがあり, 肺の影響をより受けやすいp法では心臓からのクリアランスが, 見かけ上低下しうることがその原因の一つとして考えられた. 異常の検出という点ではS法の方がより鋭敏であったが, いずれも問題点を有する方法であり, それぞれに影響しうる因子を考慮し利用することが必要と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-MIBG scintigram, Clearance from the heart, Clearance from the lung, Congestive heart failure. |
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| English |
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| Title | Evaluation of 123I - MIBG Clearance from the Myocardium ; Comparison of Two Methods - SPECT & Planar Methods |
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| Subtitle | Short Communication |
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| Authors | Masaki TSUKAMOTO*, Kouji TERADA**, Satoshi YONEYAMA*, Hirotaka TATSUKAWA*, Shuji KATOH* |
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| Authors(kana) | |
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| Organization | *Department of Internal Medicine, Murakami Memorial Hospital, Asahi University, **Department of Internal Medicine, Nantan Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 34 |
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| Number | 9 |
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| Page | 827-830 |
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| Year/Month | 1997/9 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]In 123I-metaiodobenzylguanidine(MIBG)scintigram, MIBG clearance from the heart is used to evaluate the severity of various heart diseases. There are two methods for calculating MIBG clearance. One involves planar images(planar method)and the other uses a bull's eye map(SPECT method). In 158 patients and 10 normal subjects, we compared these two methods. Fifteen minutes and 4 hours after intravenous injection of 111MBq MIBG, planar images and SPECT images were obtained. Then clearance from the heart was calculated by each method. Abnormal increase was defined as present if clearance was more than the mean + standard deviation of 10 normal subjects. Then, we examined the sensitivity with which each method could detect clearance abnormality in 158 patients. Thirty-two patients showed abnormality only on SPECT images, while planar images alone showed abnormalities in only 5 patients. The reason the SPECT method was more sensitive than the planar method may be as follows;in the case of decreased MIBG clearance from the lung, for example, in congestive heart failure, clearance by planar method is apparently decreased. Thus, the SPECT method can detect clearance abnormality more sensitively than the planar method, and if we evaluate MIBG clearance from the heart by the planar method, we must take into account MIBG clearance from the lung. |
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| Practice | Clinical medicine |
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| Keywords | 123I-MIBG scintigram, Clearance from the heart, Clearance from the lung, Congestive heart failure. |
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