| Japanese |
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| Title | N-isopropyl-p-[123I]-iodoamphetamineシンチグラフィが確定診断につながった鼻腔原発乏色素性悪性黒色腫の1症例 |
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| Subtitle | 症例報告 |
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| Authors | 戸矢和仁*1, 藤井博史*2, 冨永紳一*1, 中村佳代子*2, 小須田茂*3, 久保敦司*2, 増野博康*4, 赤塚誠哉*5 |
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| Authors(kana) | |
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| Organization | *1浦和市立病院放射線科, *2慶應義塾大学医学部放射線科, *3防衛医科大学校放射線医学講座, *4浦和市立病院耳鼻咽喉科, *5検査科病理 |
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| Journal | 核医学 |
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| Volume | 34 |
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| Number | 9 |
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| Page | 815-820 |
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| Year/Month | 1997/9 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」初回病理診断にて確定診断のつかなかった鼻腔原発の乏色素性悪性黒色腫の症例に対して, MRI, 67Gaシンチグラフィ, N-isopropyl-p-[123I]-iodoamphetamine(123I-IMP)SPECTを施行した. MRIで悪性黒色腫と診断できなかった. また67Gaシンチグラフィでは悪性リンパ腫と区別できなかった. 123I-IMPシンチグラフィでは指摘された病巣に集積を認め, 123I-IMP静注4時間後の後期像にて, その集積が著明となった. 視診上黒色を呈していなかったので乏色素性または無色素性黒色腫が予想された. 免疫組織化学的検査も施行されて最終的には, 乏色素性悪性黒色腫と診断され, 本症例において, 123I-IMP SPECT検査が確定診断につながった. 鼻腔原発悪性黒色腫では乏色素性型や無色素性型が多く, 本疾患が疑われる場合, 他画像診断より123I-IMP SPECTが有用であると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Malignant melanoma, Nasal cavity, Oligomelanotic melanoma, 123I-IMP, SPECT. |
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| English |
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| Title | Oligomelanotic Malignant Melanoma in the Nasal Cavity Diagnosed by IMP Scintigraphy |
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| Subtitle | Case Reports |
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| Authors | Kazuhito TOYA*1, Hirofumi FUJII*2, Shin-ichi TOMINAGA*1, Kayoko NAKAMURA*2, Shigeru KOSUDA*3, Atsushi KUBO*2, Hiroyasu MASHINO*4, Seiya AKATSUKA*5 |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Urawa Municipal Hospital, *2Department of Radiology, Keio University School of Medicine, *3Department of Radiology, National Defense Medical College, *4Department of Otorhinolaryngology, Urawa Municipal Hospital, *5Division of Pathology, Department of Clinical Laboratories, Urawa Municipal Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 34 |
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| Number | 9 |
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| Page | 815-820 |
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| Year/Month | 1997/9 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]MRI, 67Ga scintigraphy, and 123I-IMP-SPECT were performed in the patient with oligomelanotic malignant melanoma in the nasal cavity which is not confirmed pathologically at first. MRI failed to diagnose the tumor as malignant melanoma. It was difficult to differentiate malignant melanoma from malignant lymphoma in 67Ga scintigraphy. The remarkable accumulation of 123I-IMP was consistent with the tumor localization in the nasal cavity. This tumor uptake was thought to be oligomelanotic or amelanotic melanoma since the accumulation was more distinctive at the delayed image and since the tumor was not visibly melanotic. Finally the tumor was confirmed to be oligomelanotic melanoma by immunohistochemical examination;which was in accordance with IMP-SPECT findings. Oligomelanotic or amelanotic melanoma occurs in nasal cavity with high frequency. We report here the oligomelanotic melanoma case where IMP-SPECT was rather useful to make a pathological diagnosis than other imaging modalities. |
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| Practice | Clinical medicine |
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| Keywords | Malignant melanoma, Nasal cavity, Oligomelanotic melanoma, 123I-IMP, SPECT. |
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