Japanese
Titleトレッドミル運動負荷断層タリウム心筋シンチグラフィ (201Tl - SPECT)による6年間の心疾患長期予後の検討
Subtitle原著
Authors林克己*, 大鈴文孝*, 小須田茂**, 中村治雄*
Authors(kana)
Organization*防衛医科大学校第一内科, **放射線科
Journal核医学
Volume34
Number7
Page443-451
Year/Month1997/7
Article原著
Publisher日本核医学会
Abstract「要旨」1986年にトレッドミル運動負荷断層心筋シンチグラフィ(SPECT)を実施した117名に対し, 1993年まで追跡調査を実施し, 年齢, 性別, 冠危険因子, 運動耐容能, 運動負荷直後SPECT像での取り込みの低下スコア(E), 4時間後SPECT像での取り込みの低下スコア(L), 再分布のスコア(R)を検討した. 追跡項目は心事故の有無を検討し, 追跡可能な95名中心事故は27名(心臓死3名, 心筋梗塞1名, 経皮的冠血管拡張術16名, 冠動脈バイパス術5名, 心不全3名)であった. 心事故群と非心事故群では心筋梗塞の既往(67% vs. 18%;p<0.01), 運動耐容能(Mets)(6.8±2.8 vs. 8.1±2.6;p<0.05), E(12.1±7.3 vs. 6.8±6.7;p<0.01), L(10.3±6.4 vs. 5.8±6.4;p<0.01)に有意差があり, R(1.1±3.0 vs. 1.8±3.4)には有意差はなかった. 心事故に関し梗塞の既往および運動直後像および4時間後SPECT像での取り込みの低下スコアが予後を規定する因子であった.
Practice臨床医学:一般
KeywordsPrognosis, Treadmill exercise, 201Tl single photon emission computed tomography.
English
TitlePrediction of 6 - year Prognosis for Cardiac Event by Thallium - 201 Single - Photon Emission Computed Tomography (SPECT) with Treadmill Exercise Test
SubtitleOriginal Articles
AuthorsKatsumi HAYASHI*, Fumitaka OHSUZU*, Shigeru KOSUDA**, Haruo NAKAMURA*
Authors(kana)
Organization*Department of Medicine I, National Defense Medical College, **Department of Radiology, National Defense Medical College
JournalThe Japanese Journal of nuclear medicine
Volume34
Number7
Page443-451
Year/Month1997/7
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]To examine thallium-201 single-photon emission computed tomography(SPECT)with a treadmill exercise test can predict the long-term prognosis of patients with coronary artery disease, 95 patients(71 men, 24 women)who underwent a treadmill exercise test with thallium-201 SPECT from April to December 1986 were followed for 6 years. Three short-axis slices at the apical, mid- and basal-level were selected, and each slice was divided into eight segments. Each segment count was assigned a score according to the count range in the slice(score O, count range 76-100%;1, 51-75%;2, 26-50%;3, 1-25%;4, 0%)by evaluating the mean value of the slice. The total Tl defect score of each segment in 3 slices was summed(ΣTl defect score). The 'earlyΣTl defect score' was the ΣTl defect score 5 min after treadmill exercise, and the 'late ΣTl defect score' was ΣTl defect score measured 4 h after treadmill exercise. Cardiac events occurred in 27 of the 95 patients:cardiac death 3;myocardial infarction 1;percutaneous transluminal angioplasty 16;coronary artery bypass graft 5;congestive heart failure 3. Univariate analysis showed that previous myocardial infarction(p<0.01), exercise work load(p<0.05), early ΣTl defect score(p<0.01)and late ΣTl defect score(p<0.01)were independent predictors of the prognosis. These results suggest that thallium-201 SPECT with the treadmill exercise test could be applicable and useful to predict long term prognosis.
PracticeClinical medicine
KeywordsPrognosis, Treadmill exercise, 201Tl single photon emission computed tomography.

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