Japanese |
Title | 99mTc - ECD SPECTを用いたacetazolamide負荷反応の定量的評価法 - Response Map作成の試み - |
Subtitle | 技術報告 |
Authors | 小山帝任*, 須藤博二*, 川村宏司*, 寺岡悟見**, 緑川宏* |
Authors(kana) | |
Organization | *青森県立中央病院放射線科, **GE横河メディカルシステム株式会社 |
Journal | 核医学 |
Volume | 34 |
Number | 6 |
Page | 389-397 |
Year/Month | 1997/6 |
Article | 報告 |
Publisher | 日本核医学会 |
Abstract | 「要旨」99mTc-ECDを用いて簡便にacetazolamide負荷前後の局所脳血流量測定が行える松田・竹内らの方法において, 安静時に対する負荷時の脳血流量増加率を反応性画像(Response Map)として表現するための検討を行った. [(負荷時定量画像-安静時定量画像)/安静時定量画像×100]の演算処理を行ってResponse Mapを作成するには, マトリクス・サイズ変換にスムージングを併用した画像前処理が必要であり, 増幅した脳実質外領域のノイズ成分を除去するためにマスク処理も必要であった. 作成されたResponse Mapは, acetazolamide負荷による反応性の視覚的評価に役立ち, 病態把握や経過観察に対する有用性が示唆された. 「I. はじめに」acetazolamide負荷脳血流SPBCTの定性画像を用いて脳循環予備能の評価を行う場合には, 患部と対側健常部の左右差が指標となり予備能の低下を指摘することができる. |
Practice | 臨床医学:一般 |
Keywords | 99mTc-ECD, SPECT, rCBF, Acetazolamide, Cerebral perfusion reserve. |
English |
Title | Quantitative Evaluation of Response at Acetazolamide Test Using 99mTc - ECD SPECT ; A Trial of Production of the Response Map |
Subtitle | Technical Reports |
Authors | Tadatoh OYAMA*, Hiroji SUTOH*, Hiroshi KAWAMURA*, Satomi TERAOKA**, Hiroshi MIDORIKAWA* |
Authors(kana) | |
Organization | *Department of Radiology, Central Hospital of Aomori, **GE Yokogawa Medical Systems, Ltd. |
Journal | The Japanese Journal of nuclear medicine |
Volume | 34 |
Number | 6 |
Page | 389-397 |
Year/Month | 1997/6 |
Article | Report |
Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
Abstract | [Summary]In the method by Matsuda and Takeuchi et al. for easy regional cerebral blood flow(rCBF)measurements at pre-and post-acetazolamide tests using 99mTc-ECD, a study was done for producing the increase rate of rCBF as a response map after acetazolamide administration. To prepare the response map calculated from the arithmetic operation of[(rCBF image at administration-rCBF image at rest)/rCBF image at rest×100], the images were preprocessed by combination of matrix size conversion and smoothing techniques and then areas outside the brain were masked to remove amplified noises. The response map seemed helpful for visual evaluation of the response after acetazolamide administration, and also for understanding the disease conditions and clinical courses. |
Practice | Clinical medicine |
Keywords | 99mTc-ECD, SPECT, rCBF, Acetazolamide, Cerebral perfusion reserve. |