Japanese
Title99mTc-Tetrofosmin心拍同期心筋SPECTデータを用いた左室収縮能評価 - 左室辺縁自動抽出法による容量算出に基づく機能解析 -
Subtitle《短報》
Authors汲田伸一郎*, 趙圭一*, 水村直*, 木島鉄仁*, 石原眞木子*, 鳥羽正浩*, 井上幸平*, 隈崎達夫*, 佐野純子**, 多田祐美子**, 哲翁弥生**, 酒井俊太**, 草間芳樹***, 宗像一雄**
Authors(kana)
Organization*日本医科大学放射線科, **日本医科大学第一内科
Journal核医学
Volume34
Number4
Page237-242
Year/Month1997/4
Article報告
Publisher日本核医学会
Abstract「要旨」各種心疾患33例に99mTc-Tetrofosmin 555〜740 MBqを静注, 30〜60分後よりADAC社製2検出器型ガンマカメラVERTEXシステムを用い, 心拍同期心筋SPECTデータ収集を行った. 得られたSPECTデータより左室辺縁抽出法に基づき左室容量および左室駆出分画(LVEF)を算出, 生データより機能解析終了までおよそ3分30秒の所要時間であった. 2名の検者により任意の10症例に対し, LVEFおよび左室拡張末期容量の算出を行ったところ, 検者間の解析値の比較ではそれぞれ相関係数r=0.996, r=0.988ときわめて良好な再現性を示した. またSPECTデータより算出したLVEFは, 心プールシンチグラフィにより得られたそれとの比較にてr=0.91と良好な相関を示した. 本機能解析法は再現性, 信頼性に富み, かつきわめて短時間内の処理が可能であるため, 臨床的に有用な検査手法であると考える.
Practice臨床医学：一般
KeywordsTechnetium-99m-tetrofosmin, Gated myocardial SPECT, Left ventricular function.
English
TitleAssessment of Left Ventricular Systolic Function Derived from ECG-Gated Myocardial SPECT with 99mTC-Tetrofosmin : Automatic Determination of LV Epi- and Endocardial Surface
Subtitle- Short Communication -
AuthorsShin-ichiro KUMITA*, Keiichi CHO*, Sunao MIZUMURA*, Tetsuji KIJIMA*, Makiko ISHIHARA*, Masahiro TOBA*, Kohei INOUE*, Tatsuo KUMAZAKI*, Junko SANO**, Yumiko TADA**, Yayoi TETSUOU**, Shunta SAKAI**, Yoshiki KUSAMA**, Kazuo MUNAKATA**
Authors(kana)
Organization*Department of Radiology, **First Department of Internal Medicine, Nippon Medical School
JournalThe Japanese Journal of nuclear medicine
Volume34
Number4
Page237-242
Year/Month1997/4
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractNon-invasive assessment of ischemic heart disease requires information of both LV function and myocardial perfusion. Recently, ECG-gated myocardial SPECT with technetium-labeled radiopharmaceuticals can provide both of them. Gated myocardial SPECT were performed in thirty-three patients with cardiac disease using a two-headed rotating gamma camera system (ADAC; VERTEX), 30-60 minutes after resting injection of 555-740 MBq of 99mTc-Tetrofosmin. Then, the SPECT data were used to determine the LV epi- and endocardial surface, and LV volume for measurement of LVEF was calculated automatically. This entire computational process required only 210 seconds per 16 frame study. Inter-observer agreement of EF values obtained from gated SPECT was excellent (r=0.996, n=10, p<0.01). LVEFs obtained from gated SPECT showed good correlation to those calculated from radionuclide ventriculography (MUGA) (r=0.91, p<0.01). In conclusion, this automatic method using gated myocardial SPECT data was considered to be useful for assessment of LV function with reproducibility.
PracticeClinical medicine
KeywordsTechnetium-99m-tetrofosmin, Gated myocardial SPECT, Left ventricular function.

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