| Japanese |
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| Title | 心筋18F-FDG-SPECT画像の心筋viability評価における有用性 |
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| Subtitle | 《原著》 |
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| Authors | 佐藤秀樹*, 外山卓二*, 金古善明*, 永井良三*, 冨吉勝美**, 井上登美夫**, 遠藤啓吾**, 太田直樹***, 金沢紀雄***, 鈴木忠**** |
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| Authors(kana) | |
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| Organization | *群馬大学医学部第二内科, **群馬大学医学部核医学科, ***国立高崎病院内科, ****群馬大学医療技術短期大学部 |
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| Journal | 核医学 |
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| Volume | 34 |
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| Number | 3 |
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| Page | 137-143 |
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| Year/Month | 1997/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」目的・対象: 18F-FDG-SPECT(FDG-SPECT)を用いて陳旧性心筋梗塞例14例(男性: 女性12: 2, 62±10歳)の心筋viability評価を201Tl心筋SPECT(Tl-SPECT)および123I-BMIPP心筋SPECT(BMIPP-SPECT)と比較検討した. 方法: FDG-SPECTは, ブドウ糖負荷状態でFDGを静注し撮像した. Tl-SPECTおよびBMIPP-SPECTは安静時に撮像した. 各SPECT像を7区域に分割し, 集積程度を視覚的に4段階の欠損スコア(DS)(0=normal〜3=defect)で, また, 定量的に% uptakeを算出した. 結果: 梗塞領域の核種の集積程度は123I-BMIPP<201Tl<18F-FDGと18F-FDGが最も高く, 高度に壁運動が障害されている区域においてもFDGは他2核種よりもより集積していた. 総括: 梗塞領域の核種の集積程度はFDGが壁運動低下領域において最も高かった. 以上, 心筋viabitity評価においてFDG-SPECTは有用と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 18F-fluorodeoxyglucose, SPECT imaging, Myocardial viability, Old myocardial infarction, Regional wall motion. |
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| English |
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| Title | The Usefulness of 18F-FDG SPECT Imaging in Evaluating Myocardial Viability |
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| Subtitle | - Original Articles - |
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| Authors | Hideki SATO*, Takuji TOYAMA*, Yoshiaki KANEKO*, Ryozo NAGAI*, Katsumi TOMIYOSHI**, Tomio INOUE**, Keigo ENDO**, Naoki OTA***, Norio KANAZAWA***, Tadashi SUZUKI**** |
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| Authors(kana) | |
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| Organization | *Second Department of Internal Medicine, Gunma University School of Medicine, **Department of Nuclear Medicine, Gunma University School Medicine, ***Department of Internal Medicine, National Takasaki Hospital, ****College of Medical Care and Technology, Gunma University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 34 |
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| Number | 3 |
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| Page | 137-143 |
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| Year/Month | 1997/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We compared myocardial viability evaluated by 18F-deoxyglucose (FDG) SPECT in 14 old myocardial infarction patients with that evaluated by 201Tl SPECT and 123I-β-methyl-iodophenyl pentadecanoic acid SPECT as imaging of fatty acid metabolism. FDG-SPECT was performed after oral administration of glucose. From each SPECT image which was divided into 7 segments, the degree of accumulation of each radioisotope (RI) was visually classified into four grades of defect score (ranging from 0 as normal to 3 as severe defect). The % uptake in the same area was also quantitatively calculated. Results: The degree of accumulation of myocardial RI relative to regional wall motion. FDG is the most wide for a range of accumulation of RI of infarct area. Also, at FDG, in the area of wall motion had done a disorder, the degree of accumulation was higher than other two methods. In the infarcted area, the degree of accumulation on FDG-SPECT in the area of decreased wall motion was greater than that on the other two procedurs. These results suggest that FDG-SPECT is useful for evaluating myocardial viability. |
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| Practice | Clinical medicine |
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| Keywords | 18F-fluorodeoxyglucose, SPECT imaging, Myocardial viability, Old myocardial infarction, Regional wall motion. |
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