| Japanese |
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| Title | 123I-MIBG心筋SPECTにおける欠損領域角度 |
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| Subtitle | 《短報》 |
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| Authors | 寺田幸治*,†, 杉原洋樹**, 立川弘孝*, 計良夏哉*, 森本聡*, 井上啓司*, 加藤周司*, 中川雅夫*** |
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| Authors(kana) | |
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| Organization | *朝日大学村上記念病院内科, **京都府立医科大学放射線科, ***京都府立医科大学第二内科, †現;公立南丹病院内科 |
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| Journal | 核医学 |
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| Volume | 34 |
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| Number | 2 |
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| Page | 113-117 |
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| Year/Month | 1997/2 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」123I-metaiodobenzylguanidine(MIBG)心筋シンチグラフィにおける後下壁の集積低下を定量評価した. 非虚血性心疾患患者150例に安静時MIBG心筋シンチグラフィを施行し, MIBG静注4時間後のSPECT像ブルズアイ表示を得た. 健常心13例から作成した標準ブルズアイマップのデータをもとに, 平均値-2SD未満の有意な集積低下セグメントをblack-outしたところ, black-outされた領域は後下壁を含む扇形に近似し得た. 得られた扇形の中心角すなわち欠損領域角度(angle of defect, AOD)は, 従来からの定量的指標である心臓縦隔比やクリアランスと有意な相関関係を示した. この欠損領域角度AODは心臓交感神経機能異常を表す有用な指標であり, また心臓交感神経機能異常は非虚血各種心疾患とも後下壁から現れやすいことが示唆された. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-metaiodobenzylguanidine, Myocardial scintigraphy, Bull's eye, Infero-posterior defect, Angle of defect (AOD). |
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| English |
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| Title | Angle of Defect on 123I-MIBG Myocardial SPECT |
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| Subtitle | - Short Communication - |
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| Authors | Kouji TERADA*, Hiroki SUGIHARA**, Hirotaka TATSUKAWA*, Natsuya KEIRA*, Satoshi MORIMOTO*, Keiji INOUE*, Shuji KATOH*, Masao NAKAGAWA*** |
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| Authors(kana) | |
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| Organization | *Department of Medicine, Murakami Memorial Hospital, **Department of Radiology, ***Second Department of Medicine, Kyoto Prefectural University of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 34 |
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| Number | 2 |
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| Page | 113-117 |
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| Year/Month | 1997/2 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | The quantitative assessment of infero-posterior defect on 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy was studied in 150 patients with non-ischemic heart diseases at rest. The bull's eye map, obtained from the SPECT images at 4 hours after MIBG injection, was evaluated by generating the blacked out map which exhibits regions with reduced % uptake under mean -2SD of 13 normal controls. The blacked out regions involved infero-posterior segments and were closely resembled to the sector form. The central angle of this sector, which was named as angle of defect (AOD), significantly correlated with both the heart-to-mediastinum activity ratio (H/M) and the myocardial clearance of MIBG. Because H/M and clearance are widely used as quantitative indices in MIBG myocardial scintigraphy, these results indicate that AOD can also be used as a quantitative index of abnormal cardiac sympathetic nervous function, which is likely to appear in infero-posterior regions in non-ischemic cardiac diseases. |
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| Practice | Clinical medicine |
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| Keywords | 123I-metaiodobenzylguanidine, Myocardial scintigraphy, Bull's eye, Infero-posterior defect, Angle of defect (AOD). |
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