Japanese
Title脳炎患者に対する脳血流SPECTの有用性
Subtitle《原著》
Authors長町茂樹*, 陣之内正史*, Leo G.FLORES II*, 小玉隆男*, 糸数直哉**, 中原浩*, 大西隆*, 二見繁美*, 渡邊克司*
Authors(kana)
Organization*宮崎医科大学放射線科, **宮崎医科大学小児科
Journal核医学
Volume34
Number1
Page7-17
Year/Month1997/1
Article原著
Publisher日本核医学会
Abstract「要旨」脳炎患者17例を対象に脳血流SPECTを延べ29回施行し, MRI所見と比較検討した. 発症1週以内の急性期に評価した6例中5例(83.3%)に局所高集積域を認め, 2週以後の亜急性期〜慢性期に検査した23例中16例(69.6%)では, 局所的な低集積域を認めた. 経過観察し得た高集積19病巣中6病巣(31.6%)は経過中に低集積域に変化し11病巣(57.9%)は正常集積に回復した. 急性期〜慢性期を含めて, 初回検査時低集積を示した51病巣中17病巣(33.3%)は, 経過中に正常集積に回復した. MRIとの比較では, SPECTにて高集積を呈した18領域中8領域(44.4%)に皮質の肥厚, T2強調画像上の高信号病変が認められた. また低集積を呈した74領域中36領域(48.6%)で病巣に一致した. 皮質の肥厚, 脳萎縮, T2強調画像上の高信号病変が認められた. また, MRI上は無所見であった212領域中48領域(22.6%)にSPECT検査にて異常所見が認められた. 脳炎の病態の把握, 経過観察に脳血流SPECT検査が有用であった.
Practice臨床医学:一般
KeywordsEncephalitis, MRI, SPECT.
English
TitleUsefulness of rCBF SPECT in Patients with Encephalitis : Comparison Study With MRI
Subtitle- Original Articles -
AuthorsShigeki NAGAMACHI*, Seishi JINNOUCHI*, Leo G.FLORES II*, Takao KODAMA*, Naoya ITOKAZU**, Hiroshi NAKAHARA*, Takashi OHNISHI*, Shigemi FUTAMI*, Katsushi WATANABE*
Authors(kana)
Organization*Department of Radiology, Miyazaki Medical College, **Department of Pediatrics, Miyazaki Medical College
JournalThe Japanese Journal of nuclear medicine
Volume34
Number1
Page7-17
Year/Month1997/1
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractTwenty-nine rCBF SPECT study was done in 17 patients with encephalitis. Five of 6 patients (83.3%) showed regional high uptake in acute phase within a week after onset and 16 of 23 studies (69.6%) showed regional low uptake in subacute and chronic phase. Six of 19 lesions (31.6%) with regional high uptake changed to low uptake and 11 lesions (57.9%) improved to normal uptake on follow up studies. Seventeen of 51 lesions with low uptake (33.3%) improved to normal uptake. On the comparative study with MRI, 8 of 18 (44.4%) high uptake area showed cortical thickness or high intensity on T2 weighted images. Thirty-six of 74 low uptake area (48.6%) showed cortical thickness, brain atrophy or high intensity on T2 weighted images. Forty-eight of 212 regions (22.6%) with normal MRI findings showed abnormal accumulation of cerebral tracer on rCBF SPECT studies. rCBF SPECT was useful tool for diagnosis and follow up management in patients with encephalitis.
PracticeClinical medicine
KeywordsEncephalitis, MRI, SPECT.

【全文PDF】