| Japanese |
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| Title | 骨シンチグラフィが診断の契機となった両側副腎神経芽細胞腫の1例 |
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| Subtitle | 症例報告 |
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| Authors | 菅一能*, 清水建策*, 西垣内一哉*, 久米典彦*, 河村武彦*, 松永尚文* |
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| Organization | *山口大学医学部放射線医学講座 |
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| Journal | 核医学 |
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| Volume | 33 |
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| Number | 12 |
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| Page | 1337-1342 |
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| Year/Month | 1996/12 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 生後7か月女児の左副腎の神経芽細胞腫摘出術後に施行された骨シンチグラフィで右副腎へ骨外集積が認められ, 術前CTの見直しおよび術後経過から両側副腎発生の神経芽細胞腫であることが判明した1例を報告した. 右副腎腫瘍は123I-MIBGでも陽性描画されたが, 集積程度は片側副腎の神経芽細胞腫を摘出された他7症例の正常側副腎の集積に比し必ずしも高くなかった. 術前CTでは右副腎の腫大は軽度で有意な腫大と判定されなかった. その後CTで右副腎はさらに増大した. 神経芽細胞腫は骨シンチグラフィで骨外集積の認められる頻度が多い腫瘍であり, 両側副腎発生の神経芽細胞腫の早期診断に骨シンチグラフィが有用な場合があることが示唆された. 「I. はじめに」 神経芽細胞腫は小児悪性腫瘍の約10%を占め, 腹部固形腫瘍の中では最も頻度が高いとされる. 近年, マススクリーニングが行われ正確な診断の重要性が増してきた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Bone scintigraphy, 123I-metaiodo-benzyl-guanidine (MIBG), Neuroblastoma, Adrenal gland scintigraphy |
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| English |
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| Title | A Case with Bilateral Adrenal Neuroblastomas Detected by Bone Scintigraphy |
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| Subtitle | Case Reports |
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| Authors | Kazuyoshi SUGA, Kensaku SHIMIZU, Kazuya NISHIGAUCHI, Norihiko KUME, Takehiko KAWAMURA, Naofumi MATSUNAGA |
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| Organization | Department of Radiology, Yamaguchi University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 33 |
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| Number | 12 |
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| Page | 1337-1342 |
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| Year/Month | 1996/12 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] A 7-month-old girl, who had been resected the left adrenal neuroblastoma 20 days ago, underwent bone scintigraphy with 99mTc-HMDP to survey bone metastases. The bone scan demonstrated avid uptake in the right adrenal gland, in which 123I-MIBG also accumulated. However, the degree of 123I-MIBG uptake in the right adrenal gland was not necessary higher compared to that in the normal adrenal glands in 7 patients after resection of hemilateral neuroblastomas. Reviewing the preoperative abdominal CT, a swelling of the right adrenal gland had been overlooked because of the small size of 10×12 mm in diameter. The follow-up CT after surgery revealed a more growth of the right adrenal gland, accompanied by reelevation of urine vanilmandelic acid. This patient was thus diagnosed as bilateral neuroblastomas. Because bone scintigraphy frequently shows abnormal uptake in primary neuroblastomas, it has potentially diagnostic value for early detection of bilateral adrenal neuroblastomas. |
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| Practice | Clinical medicine |
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| Keywords | Bone scintigraphy, 123I-metaiodo-benzyl-guanidine (MIBG), Neuroblastoma, Adrenal gland scintigraphy |
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