| Japanese |
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| Title | 全身PETによるがんスクリーニングの試み |
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| Subtitle | 《原著》 |
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| Authors | 安田聖栄*, 井出満*, 高木繁治*, 正津晃* |
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| Authors(kana) | |
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| Organization | *山中湖クリニック画像診断センター |
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| Journal | 核医学 |
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| Volume | 33 |
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| Number | 10 |
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| Page | 1065-1071 |
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| Year/Month | 1996/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」全身PETでがんのスクリーニングを試みている. 1年3か月間に1,105名に計1,138回検査を施行した. 2-deoxy-2-［18F］fluoro-D-glucose(FDG)を260〜370MBq静注後45〜60分に骨盤から上顎部の範囲のemission scanを施行した. PETで肺癌2例, 大腸癌2例, 乳癌・甲状腺癌・胃癌・腎癌・悪性リンパ腫各1例の計9例(0.81%)が発見された. 悪性リンパ腫以外は手術が行われ, 全例でリンパ節転移は認められなかった. 前立腺癌3例, 膀胱癌1例, 大腸腺腫内癌2例はPETで偽陰性であった. サルコイドーシス, 慢性甲状腺炎, 肺結核腫, 耳下腺Warthin腫瘍, 慢性副鼻腔炎の各1例が偽陽性であった. 心筋のFDG高集積により画像にartifactが生じる場合があった. また腸管へのFDG集積は読影で注意を要した. 今回の検討から全身PETにより種々の臓器の悪性腫瘍が治癒切除可能な段階で発見できると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | PET, Whole-body PET, Cancer screening, 18F-FDG, Oncology. |
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| English |
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| Title | Cancer Screening with Whole-Body FDG PET |
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| Subtitle | - Original Articles - |
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| Authors | Seiei YASUDA, Michiru IDE, Shigeharu TAKAGI, Akira SHOHTSU |
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| Authors(kana) | |
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| Organization | HIMEDIC Imaging Center at Lake Yamanaka |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 33 |
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| Number | 10 |
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| Page | 1065-1071 |
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| Year/Month | 1996/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We are using whole-body positron emission tomography (PET) for cancer screening. A total of 1,105 healthy subjects have undergone PET studies 1,138 times in fifteen months. Emission scans were performed from the pelvis to the maxilla 45 to 60 minutes after intravenous administration of 260 to 370 MBq 2-deoxy-2[18F]fluoro-D-glucose (FDG). Malignant tumors were detected with PET in nine patients (0.81%): 2 lung cancers, 2 colonic cancers, 1 breast cancer, 1 thyroid cancer, 1 gastric cancer, 1 renal cancer, and 1 lymphoma. Eight of these patients underwent surgery (excepting the lymphoma patient). Lymph node metastasis was not observed in any of the eight cases and surgery was curative. PET scan results were negative in the cases of three prostatic cancers, one bladder cancer, and two colonic mucosal cancers. High FDG accumulations were noticed in benign lesions such as sarcoidosis, chronic thyroiditis, pulmonary tuberculoma, Warthin's tumor of the parotid gland, and chronic sinusitis. In some cases, image artifacts caused by intense myocardial FDG accumulations resulted in incomplete examinations of the lung. Occasionally, high FDG accumulations were observed in the bowel. Our study results suggest the possibility of using whole-body PET for detecting wide varieties of cancers in resectable stages. |
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| Practice | Clinical medicine |
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| Keywords | PET, Whole-body PET, Cancer screening, 18F-FDG, Oncology. |
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