| Japanese |
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| Title | 123I-BMIPP心筋SPECTより心筋摂取率を求める方法の検討とその意義 |
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| Subtitle | 《原著》 |
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| Authors | 岩瀬幹生*, 鳥山隆之**, 伊藤公人**, 島雄隆一郎**, 池田浩志郎**, 鈴木健***, 信田高明****, 飯田昭彦***** |
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| Authors(kana) | |
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| Organization | *豊川市民病院放射線科, **豊川市民病院内科, ***国立療養所豊橋東病院内科, ****菰野厚生病院内科, *****名古屋市総合リハビリテーションセンター放射線科 |
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| Journal | 核医学 |
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| Volume | 33 |
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| Number | 10 |
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| Page | 1043-1052 |
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| Year/Month | 1996/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」SPECTから123I-BMIPPの心筋摂取率(TU)を求める方法を検討し, 左室造影より求めた心機能(EF, CO, CI)と比較した. 対象は急性心筋梗塞42例で, PTCA後1週間以内, 1-2週間以内, 2週間-1.5か月以内, 1.5-3か月以内, 3か月以上に区分けして検討した. 胸厚(Tw)の算出は, 123Iの胸部吸収率を測定し求めた. TUは短軸断層像より心筋カウントを求め, Twにて吸収補正して早期像(E)と後期像(D)の各々の値を求めた. BMIPPの肺摂取の心筋への影響は, 最高1.76%と軽微であった. 心機能とのTU比較では, 1週間以内と3か月以上において相関があり, 3か月以上でかつD-TUの方が良好であった. TUとEF, CO, CIとでは, TUとCIが相関が良好であった. TUと心機能が, 1週間以内において相関するのはPTCA前の梗塞状態を反映し, 3か月以上にて再度相関が得られるのは, 脂肪酸代謝の回復に個人差があることが示唆された. D-TUとCIの相関が良好なのは, TUが体格の違いによる影響を受けつつも, D-TUが心機能と脂肪酸代謝を表していると思われる. |
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| Practice | 臨床医学：一般 |
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| Keywords | β-methyl-p-iodophenyl-pentadecanoic acid (123I), SPECT, Uptake, Metabolism, Cardiac index. |
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| English |
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| Title | Evaluation of a Method to Determine the Myocardial Uptake from 123I-BMIPP Myocardial SPECT and Its Significance |
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| Subtitle | - Original Articles - |
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| Authors | Mikio IWASE*, Takayuki TORIYAMA**, Masato ITOU**, Ryuichiro SHIMAO**, Koshiro IKEDA**, Takeshi SUZUKI***, Takaaki NOBUTA****, Akihiko IIDA***** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Department of Internal Medicine, Toyokawa City Hospital, ***Department of Internal Medicine, Toyohashihigashi National Hospital, ****Department of Internal Medicine, Komonokousei Hospital, *****Department of Radiology, Nagoya City Rehabilitation and Sports Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 33 |
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| Number | 10 |
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| Page | 1043-1052 |
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| Year/Month | 1996/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We examined methods of calculating myocardial uptake (TU) of 123I-BMIPP by SPECT, and compared TU to heart function (ejection fraction (EF), cardiac output (CO), cardiac index (CI)) calculated by left ventriculography. Forty-two patients with acute myocardial infarction were classified into 5 groups; within 1 week (I), from 1 to 2 weeks (II), from 2 weeks to 1.5 months (III), from 1.5 to 3 months (IV) and more than 3 months (V) after percutaneous transluminal coronary angioplasty (PTCA). Chest depth (Tw) was calculated by measuring the thoracic absorption rate of 123I. In calculating TU, the myocardial count was calculated from short-axis tomograms, and then absorption was corrected using Tw to calculate each value on early-phase image (E) and delay-phase image (D). The influence of lung uptake on myocardial count was only 1.76%. When TU was compared to heart function, there were correlations between group I and group V. Especially in group V D-TU was a significantly correlated with heart function. In heart function CI, but not EF nor CO, was significantly correlated with TU. It was suggested that the correlation between TU and heart function reflected the infarct condition before PTCA in group I, and that the individual difference in recovery of fatty acid metabolism in group V. The significant correlation between D-TU and CI suggests that D-TU reflects heart function and fatty acid metabolism, although TU is influenced by differences in physical status. |
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| Practice | Clinical medicine |
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| Keywords | β-methyl-p-iodophenyl-pentadecanoic acid (123I), SPECT, Uptake, Metabolism, Cardiac index. |
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