Japanese |
Title | 興味ある脳血流所見を示したReye症候群の1例 |
Subtitle | 《症例報告》 |
Authors | 内野謙次郎*, 長町茂樹*, 陣之内正史*, 中原浩*, Leo FLORES II*, 小玉隆男*, 大西隆*, 渡邊克司*, 糸数直哉** |
Authors(kana) | |
Organization | *宮崎医科大学放射線医学教室, **宮崎医科大学小児科学教室 |
Journal | 核医学 |
Volume | 33 |
Number | 9 |
Page | 1005-1010 |
Year/Month | 1996/9 |
Article | 報告 |
Publisher | 日本核医学会 |
Abstract | 「要旨」Reye症候群の1例において, 発症初期および慢性期に99mTc-ECD SPECTを用いて経過観察した. 発症早期では頭部X線CT上は異常を認めなかったが, 99mTc-ECD SPECT像上大脳皮質全般の集積増加が認められた. 慢性期では頭部MRI上, 全般的な脳萎縮とびまん性の白質病変が認められた. また99mTc-ECD SPECT上ではびまん性に大脳皮質の集積低下を認めた. 本症例に認められた, 高集積域から低集積域への経時的変化はReye症候群の病態の変化を反映するものと考えられ, 99mTc-ECD SPECTはその病態把握, 経過観察に有用であった. 「I. はじめに」Reye症候群はウイルス感染や薬剤などの多因子が関与してミトコンドリアの障害を起こし病理学的には脂肪肝とミトコンドリアの腫大化を示す急性脳症である. 神経症状として, 意識障害, 筋緊張異常, 痙攣があり, 臨床経過とともに様々な症状を呈する. |
Practice | 臨床医学:一般 |
Keywords | Reye syndrome, 99mTc-ECD SPECT, MRI. |
English |
Title | Reye Syndrome Evaluated by 99mTc-ECD SPECT : A Case Report |
Subtitle | |
Authors | Kenjirou UCHINO*, Shigeki NAGAMACHI*, Seishi JINNOUCHI*, Hiroshi NAKAHARA*, Leo FLORES II*, Takao KODAMA*, Takashi OHNISHI*, Katsushi WATANABE*, Naoya ITOKAZU** |
Authors(kana) | |
Organization | *Department of Radiology, Miyazaki Medical College, **Department of Pediatrics, Miyazaki Medical College |
Journal | The Japanese Journal of nuclear medicine |
Volume | 33 |
Number | 9 |
Page | 1005-1010 |
Year/Month | 1996/9 |
Article | Report |
Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
Abstract | We report a three-year-old boy with Reye syndrome evaluated by 99mTc-ECD SPECT. On acute stage, 99mTc-ECD brain SPECT disclosed diffuse high uptake in the cerebral cortex in spite of normal findings on brain X-ray CT. These lesions changed to general low uptake on the chronic state and multiple high intensity areas were shown on T2 weighted MRI image. Such a change of cerebral tracer uptake was considered to reflect the neuropathological change of Reye syndrome. 99mTc-ECD SPECT was a useful modality to diagnose Reye syndrome complementary. |
Practice | Clinical medicine |
Keywords | Reye syndrome, 99mTc-ECD SPECT, MRI. |