| Japanese |
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| Title | 運動負荷誘発心筋虚血と心機能障害の関連 : 99mTc-Tetrofosmin心筋血流画像と心機能画像の同時評価による検討 |
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| Subtitle | 《原著》 |
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| Authors | 今井嘉門*, 芝田貴裕*, 小川洋司*, 堀江俊伸* |
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| Organization | *埼玉県立小原循環器病センター循環器科 |
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| Journal | 核医学 |
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| Volume | 33 |
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| Number | 9 |
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| Page | 981-989 |
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| Year/Month | 1996/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」心筋虚血と心機能障害との詳細な検討はヒトでは少ない. 健常者および冠動脈疾患患者で運動負荷99mTc-tetrofosmin心筋シンチグラフィを行い, 心筋血流障害と心機能障害との関連を検討した. 心機能は初回循環法で, 心筋血流はSPECT画像で記録した. 対象は冠病変のない36症例(CAD(-)), 心筋梗塞症を除外した冠動脈疾患患者32症例である. 後者はさらに運動負荷時の心筋血流障害のextent score(ES)により3群: ES<10%群(n=15), ES=10-20%群(n=7), ES>20%群(n=10)に区分した. 運動負荷時の左室駆出率は, CAD(-)群61.7±5.3%, ES<10%群59.0±5.8%, ES=10-20%群57.4±6.6%, ES>20%群47.4±10.5%で, ES>20%群は他群より有意に低値であった. 心筋血流と心機能との同時評価により, 運動で誘発された血流障害が左室の20%以上に達した時に, 有意な左心機能障害が生ずることが明らかになった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Myocardial ischemia, Left ventricular dysfunction, 99mTc-tetrofosmin, Simultaneous assessment. |
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| English |
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| Title | Relationship between Exercise Induced Ischemia and Left Ventricular Dysfunction ; Simultaneous Assessment of Perfusion and Function Images with 99mTc-Tetrofosmin Myocardial Scintigraphy |
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| Subtitle | - Original Articles - |
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| Authors | Kamon IMAI, Takahiro SHIBATA, Hiroshi OGAWA, Toshinobu HORIE |
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| Authors(kana) | |
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| Organization | Department of Cardiology, Saitama-Ohara Cardiovascular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 33 |
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| Number | 9 |
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| Page | 981-989 |
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| Year/Month | 1996/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | The propose of this study was to evaluate the relationship between exercise induced ischemia and left ventricular dysfunction, ergometer exercise 99mTc-tetrofosmin myocardial scintigraphy was performed using one day protocol (exercise/rest). Subjects consisted or 68 patients without previous myocardial infarction; without coronary artery disease (CAD) (n=36) and with CAD (n=32). Perfusion and function images were evaluated simultaneously. Perfusion image was taken by single photon emission tomography (SPECT). Quantitative analysis was performed with normal data-base. The area of abnormal perfusion, less than normal lower limits, was named as extent score (ES). Left ventricular ejection fraction (LVEF) was measured by first-pass study. According to ES on stress image, 32 patients with CAD were divided into 3 groups; ES<10% (n=15), ES=10-20% (n=7) and ES>20% (n=10). LVEF at rest among 4 groups were not different. LVEF at peak exercise was 61.7+/-5.3% in CAD (-), 59.0+/-5.8% in ES<10%, 57.4+/-6.6% in ES=10-20% and 47.4+/-10.5% in ES>20%. LVEF in ES>20% at peak exercise was lowest significantly. Thus, simultaneous perfusion and function images were evaluated for the relationship between exercise induced ischemia and left ventricular dysfunction. If extent score on stress image was more than 20% of left ventricle, significant left ventricular dysfunction was observed. |
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| Practice | Clinical medicine |
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| Keywords | Myocardial ischemia, Left ventricular dysfunction, 99mTc-tetrofosmin, Simultaneous assessment. |
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