| Japanese |
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| Title | 肺結核後遺症における肺シンチグラムの半定量的評価 |
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| Subtitle | 原著 |
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| Authors | 内田耕*, 宮坂隆*, 中山浩之*, 菅沼保明*, 沈在俊*, 高橋秀樹**, 高野政明**, 河田兼光*** |
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| Authors(kana) | |
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| Organization | *東邦大学医学部第二内科, **大森病院中央放射線RI診断部, ***国立療養所南横浜病院内科 |
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| Journal | 核医学 |
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| Volume | 33 |
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| Number | 7 |
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| Page | 753-757 |
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| Year/Month | 1996/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 肺結核後遺症ではPaO2の良好な症例が呼吸不全に陥り, しばしば治療によって低酸素血症のない状態まで回復し, 肺気腫とは異なった臨床経過をとる. われわれは肺結核後遺症の肺血流分布を定量的に求め, 慢性閉塞性肺疾患 (COPD) のそれと比較した. 肺結核後遺症9例, COPD 21例において, 換気 (133Xeガス) は肺容量を表すよう, 血流 (99mTc-MAA) はカットオフレベル70%の領域に関心領域を設定してその画素数を求め, それぞれL, P70とした. 肺容量に対する血流の割合 (P70/L) の平均は肺結核後遺症0.159±0.072, COPD 0.103±0.036と肺結核後遺症で有意に高値をとった (p<0.05). 肺結核後遺症では肺容量は減少するが, 肺血流量が多い領域の面積が大きいため, P70/Lは高値をとったと考えられる. 逆に, COPDでは肺容量は保たれるが, 肺血流は最も血流が多い領域のカウントの70%以下の低い血流を有する領域が大部分であるため, P70/Lが低値をとったものと推測された. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-MAA, 133Xe gas, Pulmonary tuberculosis sequelae, Chronic obstructive pulmonary disease, Semiquantitative analysis of perfusion scintigram. |
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| English |
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| Title | An Application of Semiquantitative Analysis of Pulmonary Scintigram to Pulmonary Tuberculosis Sequelae |
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| Authors | Kou UCHIDA*, Takashi MIYASAKA*, Hiroyuki NAKAYAMA*, Yasuaki SUGANUMA*, Jae Joon SIM*, Kanemitsu KAWATA**, Hideki TAKAHASHI***, Masaaki TAKANO*** |
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| Authors(kana) | |
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| Organization | *Second Department of Internal Medicine, Toho University School of Medicine, **Minami-Yokohama National Chest Hospital, ***Division of Nuclear Medicine, Toho University Ohmori Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 33 |
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| Number | 7 |
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| Page | 753-757 |
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| Year/Month | 1996/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We performed ventilation-perfusion scintigraphy in 13 patients with pulmonary tuberculosis sequelae and 21 with chronic obstructive pulmonary disease. We used 99mTc-MAA for perfusion scintigram and 133Xe gas for ventilation scintigram. We added the radioactivities during the rebreathing phase of the ventilation scintigram to make a computerized image of the lung volume. Regions of interest (ROIs) were derived from radioactivities on each image. ROIs included each whole lung on lung volume (L) image and areas where radioactivity was greater than 70% of the highest radioactivity on perfusion (P70) image. We counted the area of ROIs on L and P70, and used the ratio of perfusion to lung volume (P70 / L) as a parameter of pulmonary perfusion. P70 / L in patients with pulmonary tuberculosis sequelae was significantly higher than that in those with COPD. This suggested that the area of high pulmonary perfusion is larger in the patients with pulmonary tuberculosis sequelae as compared with those with COPD. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-MAA, 133Xe gas, Pulmonary tuberculosis sequelae, Chronic obstructive pulmonary disease, Semiquantitative analysis of perfusion scintigram. |
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