| Japanese |
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| Title | 小脳梗塞によるテント上領域へのremote effectの評価 : 99mTc-HM-PAO SPECTを用いた半定量的検討 |
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| Subtitle | 原著 |
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| Authors | 広瀬義晃*, 林田孝平*, 福岡周司*, 石田良雄*, 西村恒彦** |
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| Organization | *国立循環器病センター放射線診療部, **大阪大学医学部トレーサ情報解析 |
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| Journal | 核医学 |
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| Volume | 33 |
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| Number | 7 |
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| Page | 705-710 |
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| Year/Month | 1996/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 小脳梗塞におけるテント上領域へのremote effectを99mTc-HM-PAO SPECTを用いて半定量的に検討した. 対象は片側性小脳梗塞18例 (男女比16 : 2, 平均年齢62歳) である. SPECTは99mTc-HM-PAO 740MBqを静注し, リング型頭部専用SPECT装置でOM lineに平行に撮像した. 小脳, 視床, 基底核, 上下前頭葉, 側頭葉, 頭頂葉, 後頭葉に関心領域を設定し, 非対称性指数 (Asymmetry Index : AI) を求めた. テント上各領域のAIは-0.64±2.74% (後頭葉) から+1.04±2.03% (上前頭葉) の間にあり平均+0.27%と小さく, 小脳とテント上の各領域のAIは相関しなかった (r=-0.32〜+0.38). さらに, 小脳梗塞の大きさとも関連はなかった. 急性・亜急性期では慢性期に比し, AIに有意差はなかったものの, テント上領域のAIは大きかった. 小脳梗塞によるテント上領域へのremote effectは, 小脳から視床を介して大脳に至る神経回路である小脳視床皮質路に起因することが考えられるが, 99mTc-HM-PAO SPECTでは検出は困難であった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Cerebellar infarction, Brain SPECT, Remote effect, Crossed hemispheric hypoperfusion, 99mTc-HM-PAO. |
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| English |
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| Title | Evaluation of Remote Effect to Supratentorial Areas in Cerebellar Infarction : A Semiquantitative Analysis Using 99mTc-HM-PAO SPECT |
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| Authors | Yoshiaki HIROSE*, Kohei HAYASHIDA*, Shuji FUKUOKA*, Yoshio ISHIDA*, Tsunehiko NISHIMURA** |
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| Organization | *Department of Radiology, National Cardiovascular Center, **Division of Tracer Kinetics, Osaka University Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 33 |
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| Number | 7 |
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| Page | 705-710 |
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| Year/Month | 1996/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We studied 18 patients with unilateral cerebellar infarction to investigate its remote effect to the supratentorial areas with 99mTc-HM-PAO SPECT. Asymmetry indexes (AI) were calculated in the cerebellum and in seven supratentorial areas (thalamus, basal ganglia, superior and inferior frontal areas, temporal area, parietal area and occipital area). Mean AIs of supratentorial areas ranged from -0.64+-2.74% to +1.04+-2.03%. In cerebellar infarction of acute or subacute phase, the mean AI showed larger values (+1.13%) than that of chronic phase (+0.21%), but this difference did not reach statistical significance. There was no significant difference among supratentorial AIs grouped according to cerebellar infarction size. There was also no significant correlation among AIs of cerebellar and the supratentorial areas (r=-0.32 to +0.38). Crossed hemispheric hypoperfusion is thought to be related to the interruption of cerebellocortical tracts. We concluded that the detection of the remote effect to supratentorial areas in cerebellar infarction was difficult with 99mTc-HM-PAO SPECT. |
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| Practice | Clinical medicine |
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| Keywords | Cerebellar infarction, Brain SPECT, Remote effect, Crossed hemispheric hypoperfusion, 99mTc-HM-PAO. |
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