Japanese
Title99mTc - MIBI心拍同期心筋シンチグラフィを用いた左室拡張機能評価 - 1スライス抽出による簡便法の試み -
Subtitle短報
Authors鳥羽正浩*, 汲田伸一郎*, 水村直*, 趙圭一*, 木島鉄仁*, 高浜克也*, 隈崎達夫*
Authors(kana)
Organization*日本医科大学放射線科
Journal核医学
Volume33
Number4
Page409-413
Year/Month1996/4
Article報告
Publisher日本核医学会
Abstract「要旨」99mTc-MIBI心拍同期心筋シンチグラフィを用いた左室拡張機能評価に関し検討を行った. 各種心疾患29例に安静時に99mTc-MIBI 740MBqを静注し, 1時間後より心拍同期SPECTデータを収集した. 左室短軸像中央部1スライスの各16分割像それぞれの心筋部分全体に対し関心領域を設定, その1ピクセルあたりのカウント数を求め, Phase Count Curveを作成し, 視覚的にパターンにより分類した. 次いで新しい拡張能評価のパラメータとして, 収縮末期から拡張末期までを3等分し, 最初の1/3におけるカウント減少率を1/3 Count Decreasing Fraction(1/3 CDF)として算出し, 心プールシンチグラフィによる拡張能指標である1/3Filling Fraction, Peak Filling Rateと比較したところ, 前者とはr=0.61, 後者とはr=0.58と相関が認められた. 本法は短軸像1スライスのみを用いた簡便な方法であり, 既存の拡張能指標をよく反映したことから, 臨床応用可能かつ有用な解析法と考察される.
Practice臨床医学：一般
Keywords99mTc-MIBI, Gated SPECT, Diastolic function.
English
TitleEvaluation of Left Ventricular Diastolic Function Using Gated SPECT with 99mTc - MIBI
SubtitleShort Communication
AuthorsMasahiro TOBA, Shin-ichiro KUMITA, Sunao MIZUMURA, Keiichi CHO, Tetsuji KIJIMA, Katsuya TAKAHAMA, Tatsuo KUMAZAKI
Authors(kana)
OrganizationDepartment of Radiology, Nippon Medical School
JournalThe Japanese Journal of nuclear medicine
Volume33
Number4
Page409-413
Year/Month1996/4
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]Development of 3 head SPECT system and 99mTc-labeled radiopharmaceuticals enable us to evaluate left ventricular systolic function on the basis of once gated SPECT routine. This study was focused on assessment of left ventricular diastolic function using 99mTc-MIBI gated SPECT data. Twenty nine patients with ischemic heart diseases underwent 99mTc-MIBI gated SPECT and 99mTc-HSAD ventriculographic assessment of left ventricular diastolic function within 1 month. Region of interests(ROI), simultaneously calculating counts per pixel within ROI, were placed over whole myocardium of 16 serial phasic images reconstructed from gated SPECT data, following selection of the central slice within short axial images. Then, 29 patients were classified into 3 patterns of phase count curve(normal, mixed, and delayed relaxation=diastolic dysfunction). Moreover, 1/3 Count Decreasing Fraction(1/3 CDF)was calculated on the same concept as 1/3 FF. The curve pattern showed significant differences between normal and abnormal group divided on the basis of established indices such as 1/3 FF and PFR, and 1/3 CDF has correlations with 1/3 FF(r=0.61)and PFR(r=0.58). We concluded that the new parameters drawn from 99mTc-MIBI gated SPECT data might be feasible for evaluation of diastolic function.
PracticeClinical medicine
Keywords99mTc-MIBI, Gated SPECT, Diastolic function.

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