Japanese
Title201TlCl retentionをパラメータとしたfunctional imageによる肺癌診断 - 放射線治療後の肺癌を中心にして -
Subtitle原著
Authors吉村尚子*, 福本光孝*, 赤木直樹**, 吉田祥二*
Authors(kana)
Organization*高知医科大学放射線科, **放射線部
Journal核医学
Volume33
Number4
Page383-390
Year/Month1996/4
Article原著
Publisher日本核医学会
Abstract「要旨」201Tl SPECTによる肺癌の診断においてretention index(以下R. I. とする)は利波らによって確立された方法であるが, われわれは201Tl retentionの新しいパラメータを考案し, そのfunctional image(以下F. I. とする)を作成し, 照射後の肺癌再発の診断において, 画像上viable lesionを陽性像として描出させる試みを行った. まず原発孤立性肺腫瘍に対しての本法による正診率は17症例(18病変)においてsensitivity 84.6%, specificity 80.0%, accuracy 83.3%であった. 腫瘍径が2.0cm以上あり, 利波らによるR. I. が12.7以上あればF. I. で陽性像として描出可能であった. 照射後による二次性変化にマスクされた22例(23病変)の症例については, sensitivity 80.0%, specificity 92.3%, accuracy 87.0%の結果が得られ, 再燃, 再発の診断に本法の有用性がみられた.
Practice臨床医学:一般
KeywordsLung cancer, 201Tl SPECT, 201TI retention, Functional image, Radiation fibrosis.
English
TitleDiagnosis of Lung Cancer Using Functional Image of 201Tl SPECT with Parameter of 201Tl Retention - Evaluation of Its Applicability to Post Irradiated Lung Cancer -
SubtitleOriginal Articles
AuthorsNaoko YOSHIMURA, Mitsutaka FUKUMOTO, Naoki AKAGI, Shoji YOSHIDA
Authors(kana)
OrganizationDepartment of Radiology, Kochi Medical School
JournalThe Japanese Journal of nuclear medicine
Volume33
Number4
Page383-390
Year/Month1996/4
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]Thallium-201(201Tl)SPECT is a useful method for detecting lung cancer. Moreover, the 201Tl Retention Index(R. L. )reported by Tonami et al is now available for differentiating pulmonary lung cancer from benign lesions. The diagnosis of recurrent tumors is, however, difficult to establish as they are often shaded by radiation pneumonitis or fibrosis. Therefore, we employed functional images(F. I. )obtained using as parameter a modified version of the R. I. First we indicated the statistical value of untreated solitary lung tumor as follows : sensitivity 84.6%, specificity 80.0%, and accuracy 83.3%. In our assessment, the lesions with tumor size over 2.0cm and R. L. by Tonami et al over 12.7 were detected as positive images. Secondly in assessment of 22 cases(23lesions)of post irradiated lung cancer, the results obtained were : sensitivity 80.0%, specificity 92.3%, and accuracy 87.0%. 201Tl SPECT functional images seem to be useful for the diagnosis of recurrent lung cancer by shaded radiation pneumonitis and fibrosis.
PracticeClinical medicine
KeywordsLung cancer, 201Tl SPECT, 201TI retention, Functional image, Radiation fibrosis.

【全文PDF】