| Japanese |
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| Title | 全身播種型非定型抗酸菌症の骨シンチグラムで多発性異常集積のみられた2症例 |
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| Subtitle | 症例報告 |
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| Authors | 佐々木義明*, 今井照彦*, 大石元*, 打田日出夫*, 塚口勝彦**, 森川高司**, 成田亘啓** |
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| Organization | *奈良県立医科大学腫瘍放射線科・放射線科, **第二内科 |
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| Journal | 核医学 |
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| Volume | 33 |
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| Number | 3 |
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| Page | 267-272 |
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| Year/Month | 1996/3 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」まれな疾患である全身播種型非定型抗酸菌症の多発性骨病変の範囲の検索に骨シンチグラムが有用であった2症例を経験した. 2症例ともに女性で起因菌はM. avium intracellulare complexであった. 過労が発症誘因と考えられ, 細胞性免疫の低下も示唆された. 骨シンチグラム所見では全身性に多発性の異常集積が認められた. 確定診断は生検によって得られたが, 本症の骨シンチグラム所見の鑑別診断の第一に悪性腫瘍の骨転移をあげる必要があると思われた. 2症例とも抗結核薬の治療により自覚症状や炎症反応は改善した時点においても骨シンチグラムの異常集積は残存した. 本シンチグラムによる治療効果判定の際には異常集積が炎症反応の改善よりも遷延する点を留意する必要があると思われた. 「I. はじめに」非定型肺抗酸菌症はその98%以上が肺内病変で, 肺外病変をきたすことは少ないとされている. |
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| Practice | 臨床医学：一般 |
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| Keywords | Generalized disseminated atypical Mycobacterium, Bone scintigraphy. |
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| English |
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| Title | Two Cases of Generalized Disseminated Atypical Mycobacterium Showing Multiple Accumulations on Bone Scintigraphy |
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| Subtitle | Case Report |
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| Authors | Yoshiaki SASAKI**, Teruhiko IMAI*, Hajime OHISHI*, Hideo UCHIDA*, Katsuhiko TSUKAGUCHI**, Takashi MORIKAWA**, Nobuhiro NARITA** |
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| Authors(kana) | |
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| Organization | *Department of Oncoradiology and Radiology, **Second Department of Internal Medicine, Nara Medical University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 33 |
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| Number | 3 |
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| Page | 267-272 |
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| Year/Month | 1996/3 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] For determining the spread of multiple bone lesions in generalized disseminated atypical mycobacteriosis, a rare disease, bone scintigraphy was found useful in our two patients. They were both female, and the pathogenic microbe was M. avium intracellulare complex. The disease appeared to have been induced by defatigation. The depression of cellular immunocompetence was also suspected to be responsible. Bone scintigraphy disclosed multiple abnormal accumulations systemically. The definitive diagnosis in these cases was established by biopsy. In differential diagnosis of this disease by bone scintigraphy, bone metastasis of a malignant tumor was considered of primary importance. Although antitubercular chemothelapy resulted in improvement of subjective symptoms and inflammation, abnormal accumulations persisted. There was necessity for taking notice that in the decision of the treatment effect of this disease, improvement of abnormal accumulations on bone scintigraphy was delayed that of inflammatory reaction. |
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| Practice | Clinical medicine |
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| Keywords | Generalized disseminated atypical Mycobacterium, Bone scintigraphy. |
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