| Japanese |
|---|
| Title | 123I - BMIPPダイナミックSPECTで逆拡散を認めた拡張型心筋症の一例 |
|---|
| Subtitle | 症例報告 |
|---|
| Authors | 吉田勢津*, 小林秀樹*, 井口信雄*, 井上征治**, 牧正子*, 細田瑳一**, 日下部きよ子* |
|---|
| Authors(kana) | |
|---|
| Organization | *東京女子医科大学放射線科, **循環器内科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 33 |
|---|
| Number | 3 |
|---|
| Page | 261-266 |
|---|
| Year/Month | 1996/3 |
|---|
| Article | 報告 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」123I-BMIPP dynamic SPECTにおいて下壁に逆拡散を認めた拡張型心筋症の一例を経験した. 28歳女性. 2次性心筋症を疑わせる所見はなく, 心エコー, 心カテーテルで左室の著明な拡大と壁運動のびまん性低下所見を認め, 正常冠動脈所見と心筋生検から拡張型心筋症と診断した. 201Tl像では左室の拡大, 不均一な集積が見られ, 投与15分後BMIPP像では, 201Tlに比して, 下壁に集積低下が認められた. BMIPP静注2分後から施行したDynamic SPECT像では, 静注直後に下壁を含め全体に集積を認めたが, 10分の経過で徐々に下壁を中心として集積低下を示し, 逆拡散の所見が認められた. 虚血性心疾患のみならず拡張型心筋症症例でも123I-BMIPPの逆拡散の所見が認められ, 同所見は心筋障害による代謝異常を示していると考えられた. 「I. はじめに」β-methyl-(123I)-iodophenylpentadecanoic acid(以下123I-BMIPPと略)心筋シンチグラフィは脂肪酸代謝を反映するトレーサとして開発され, 虚血性心疾患を対象にその有用性が評価されている. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | β-methyl-(123I)-iodophenylpentadecanoic acid(123I-BMIPP), Dilated cardiomyopathy(DCM), Back diffusion, Fatty acid metabolism, Dynamic SPECT. |
|---|
| English |
|---|
| Title | A Case of Dilated Cardiomyopathy with Early Back - diffusion of 123I - BMIPP |
|---|
| Subtitle | Case Report |
|---|
| Authors | Setsu YOSHIDA*, Hideki KOBAYASHI*, Nobuo IGUCHI*, Seiji INOUE**, Masako MAKi*, Saichi HOSODA**, Kiyoko KUSAKABE* |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology, Tokyo Women's Medical College, **The Heart Institute of Japan, Tokyo Women's Medical College |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 33 |
|---|
| Number | 3 |
|---|
| Page | 261-266 |
|---|
| Year/Month | 1996/3 |
|---|
| Article | Report |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary]A 28-year-old woman was pointed out cardiomegaly and diffuse hypokinesis of left ventricle by ultrasonography in community hospital. Coronary angiography showed normal coronary artery and, left ventriculography revealed diffuse hypokinesis(LVEF 40%). She was diagnosed idiopathic dilated cardiomyopathy by myocardial biopsy and other clinical information. Myocardial scintigraphy with 201Tl revealed dilatation of left ventricle and diffuse inhomogeneous accumulation of 201Tl.Dynamic 123I-BMIPP SPECT image 2 minutes after injection showed BMIPP accumulation in all segment, though, static image 15 minutes after injection indicated reduced BMIPP accumulation. These findings suggested existence of the early back-diffusion in inferior segment. Early back-diffusion of BMIPP may become a marker of abnormal fatty acid metabolism in patient with dilated cardiomyopathy. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | β-methyl-(123I)-iodophenylpentadecanoic acid(123I-BMIPP), Dilated cardiomyopathy(DCM), Back diffusion, Fatty acid metabolism, Dynamic SPECT. |
|---|