| Japanese |
|---|
| Title | 冠動脈疾患におけるATP負荷99mTc - MIBI心筋シンチグラフイの診断的有用性 |
|---|
| Subtitle | 原著 |
|---|
| Authors | 熊野正士* |
|---|
| Authors(kana) | |
|---|
| Organization | *愛媛大学医学部放射線科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 33 |
|---|
| Number | 2 |
|---|
| Page | 153-159 |
|---|
| Year/Month | 1996/2 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」アデノシン三燐酸二ナトリウム(ATP)負荷99mTc-MIBI心筋シンチグラフィの安全性および診断能について検討した. ATPは0.16mg/kg/minで5分間投与し, 負荷/安静の一日法を用いた. 対象は虚血性心疾患が疑われた100例で, このうち63例に冠動脈造影を施行した. 100例中副作用の出現は66%に認めたが, 治療を要したものはなく, 全例で検査は遂行できた. 本法の症例ごとのsensitivity, specificityおよびaccuracyは, 97%(38/39), 71%(17/24)および87%(55/63)であり, 病変枝については, それぞれ92%(57/62), 89%(113/127)および90%(170/189)であった. 99mTc-MIBI心筋SPECTでは肝への集積が下後壁のアーチファクトの原因となるが, ATP負荷では肝への集積が高く, アーチファクト軽減のため撮像開始時間の延長が必要であった. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Coronary artery disease, ATP, 99mTc-MIBI, Myocardial SPECT. |
|---|
| English |
|---|
| Title | 99mTc - MIBI Myocardial Tomography with Intravenous Infusion of Adenosine Triphosphate in the Diagnosis of Coronary Artery Disease |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Seishi KUMANO |
|---|
| Authors(kana) | |
|---|
| Organization | Department of Radiology, Ehime University School of Medicine |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 33 |
|---|
| Number | 2 |
|---|
| Page | 153-159 |
|---|
| Year/Month | 1996/2 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary]To evaluate its feasibility, safety and diagnostic accuracy, 99mTc-MIBI myocardial tomography with adenosine triphosphate(ATP)infusion(0.16mg/kg/min for 5 min)was performed 100 consecutive patients using the stress/rest one day protocol. None of the patients required treatment with aminophylline during the study. The sensitivity and specificity for detecting patients with coronary artery disease were 97%and 71%, respectively. Those for detecting individual coronary lesion(>=75%stenosis)were 92%and 89%, respectively. The high hepatic uptake of 99mTc-MIBI causes artifactual perfusion defects in the inferior myocardial wall, particularly on ATP stress images. In order to reduce this artifactual phenomenon, the interval time between injection and stress imaging must be increased. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Coronary artery disease, ATP, 99mTc-MIBI, Myocardial SPECT. |
|---|