| Japanese |
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| Title | 結節性甲状腺腫の良・悪性の鑑別診断における201Tlシンチグラフィの後期像の撮像時間と診断能に関する検討 |
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| Subtitle | 原著 |
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| Authors | 三木徹生*, 中條政敬*, 中別府良昭* |
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| Organization | *鹿児島大学医学部放射線科 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 12 |
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| Page | 1347-1353 |
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| Year/Month | 1995/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」結節性甲状腺腫の良・悪性鑑別診断の際, 1時間と3時間後像のいずれが201Tl後期像として, より有用か検討した. 方法は83例における良性48, 悪性38病変の201Tl集積性を5分後像で集積(-), (±), (+), (++)に分け, (±)以上の集積例は5分後像の病変対正常部の相対集積に比し, 後期像での集積の推移を減少, 不変, 増加のパターンに分けた. その結果, (-)と減少病変は良性[1時間 : 95%(35/37), 3時間 : 85%(39/46)], 増加病変は悪性[1時間 : 96%(27/28), 3時間 : 91%(21/23)]の可能性が高く, 不変病変はequivocal[悪性は1時間 : 43%(9/21), 3時間 : 59%(10/17)]であり, 統計学的には1時間後像で良・悪性はより分離した. 悪性病変検出には, 1時間後像で不変と増加を悪性, その他を良性とする診断基準が, 悪性除外診断予測能と悪性有病正診率が各々95%で最も有用であった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thyroid gland, 201TlCl, Scintigraphy, Thyroid tumor, Delayed image. |
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| English |
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| Title | Study on Different Imaging Time of Late 201Tl Thyroid Imaging to Differentiate Malignant from Benign Thyroid Nodules |
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| Authors | Tesshou MIKI, Masayuki NAKAJO, Yoshiaki NAKABEPPU |
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| Authors(kana) | |
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| Organization | Department of Radiology, Faculty of Medicine, Kagoshima University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 12 |
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| Page | 1347-1353 |
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| Year/Month | 1995/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]This study was undertaken to clarify better time to initiate the late 201Tl thyroid imaging to differentiate malignant thyroid nodules from benign ones. Thyroid images were obtained at 5 min, 1 and 3 hr after i.v. injection of 74 MBq of 201Tl chloride. The early (5 min) and late (1 or 3 hr) 201Tl images were compared in pathologically proven 38 malignant and 48 benign nodules of 83 patients. The lesion activity (LA) on the early image was visually graded as no uptake (-), slight uptake less than the surrounding thyroid tissue uptake (STTU)(+-), uptake equal to the STTU(+), and uptake more than the STTU(++). The change of LA relative to the STTU from the early image to the late image was visually graded as decreasing(D), unchanged (U) or increasing (I) pattern when the LA was (+-) to (++). The benign or malignant possibility at 1 hr and 3 hr in each lesion pattern was as follows : When the LA was (-) or D, the benign possibility was 95%(35/37) and 85%(39/46). When the LA was I, the malignant possibility was 96%(27/28) and 91%(21/23). When the LA is U, the diagnosis was equivocal : malignancy ; 43%(9/21) at 1 hr and 59%(10/17) at 3 hr. The positive LA had a tendency to decrease with time irrespective of tumor character. The 1 hr image was statistically better than the 3 hr image as a late image. Comparative diagnosis of 5 min and 1 hr images with the criteria of I and U lesions being malignant and others being benign seems to be the best not to overlook malignant nodules : negative predictive value 95% and sensitivity 95%. |
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| Practice | Clinical medicine |
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| Keywords | Thyroid gland, 201TlCl, Scintigraphy, Thyroid tumor, Delayed image. |
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