| Japanese |
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| Title | ジエチレントリアミン五酢酸インジウム標識ヒト免疫グロブリンG (111In-DTPA-IgG) を用いた炎症・感染イメージングの有用性 |
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| Subtitle | 技術報告 |
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| Authors | 鐘ヶ江香久子*, 伊藤和夫*, 塚本江利子*, 加藤千恵次*, 中駄邦博*, 望月孝史*, 志賀哲*, 古舘正從* |
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| Authors(kana) | |
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| Organization | *北海道大学医学部核医学講座 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 11 |
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| Page | 1263-1268 |
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| Year/Month | 1995/11 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」炎症および感染が疑われた10症例にジエチレントリアミン五酢酸インジウム標識ヒト免疫グロブリンG(111In-DTPA-IgG)シンチグラフィを施行し, その集積に関し検討した. 肺炎, 頬部術後炎症, 顎下部膿瘍および膝蓋腱断裂手術後の4例が陽性, 脊椎の陳旧性肉芽変化, 悪性胸膜中皮腫および異常病巣の検出されなかった各1例合計3例が陰性, 原発不明の骨転移, 脛骨壊死および消化管からの蛋白漏出の3例で偽陽性となった. 本検査における感度, 特異性, 正確度, 陽性予測度および陰性予測度はそれぞれ100%(4/4), 50%(3/6), 70%(7/10), 57.1%(4/7)および100%(3/3)であった. 111In-DTPA-IgGは炎症および感染巣の検出に有用である. |
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| Practice | 臨床医学：一般 |
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| Keywords | 111In polyclonal IgG, Infection, Inflammation. |
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| English |
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| Title | Imaging of Infectious and Inflammatory Foci Using 111In-DTPA-IgG |
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| Authors | Kakuko KANEGAE, Kazuo ITOH, Eriko TSUKAMOTO, Chietsugu KATO, Kunihiro NAKADA, Takafumi MOCHIZUKI, Toru SHIGA, Masayori FURUDATE |
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| Authors(kana) | |
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| Organization | Department of Nuclear Medicine, Hokkaido University, School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 11 |
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| Page | 1263-1268 |
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| Year/Month | 1995/11 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]We performed radionuclide scanning after intravenous administration of 80 MBq of 111In-labeled nonspecific polyclonal human immunoglobulin G (111In-DTPA-IgG). Serial scintigrams were acquired at 6, 24, 48, and 72 hr after injection in 10 patients suspected of having inflammation and/or infection. In 5 patients, the results of scintigraphy were verified with intraoperative cultures or biopsy. The values were as follow : sensitivity : 100%(4/4) ; specificity 50%(3/6) ; accuracy : 70%(7/10) ; positive predictive value : 57.1%(4/7) ; and negative predictive value : 100%(3/3). The results indicate that 111In-DTPA-IgG scintigraphy is certainly a promising method for the detection of inflammation and/or infection. |
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| Practice | Clinical medicine |
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| Keywords | 111In polyclonal IgG, Infection, Inflammation. |
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