| Japanese |
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| Title | 術前後で123I-MIBG心筋シンチグラム所見を検討し得た褐色細胞腫の1例 |
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| Subtitle | 症例報告 |
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| Authors | 松本雄賀*, 杉原洋樹**, 伊藤一貴*, 寺田幸治*, 谷口洋子*, 大槻克一*, 中田徹男*, 牛嶋陽**, 前田知穂**, 中川雅夫* |
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| Authors(kana) | |
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| Organization | *京都府立医科大学第二内科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 9 |
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| Page | 1023-1028 |
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| Year/Month | 1995/9 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」褐色細胞腫の1例の術前後に123I-MIBG心筋シンチグラフィを施行した. 本症例では, 心電図, 心臓超音波, 201Tl心筋シンチグラム等の諸検査上異常所見を認めず, 心機能異常, 心肥大, 心筋虚血は存在しないと考えられた. しかし, 123I-MIBG心筋シンチグラムでは下後壁の集積低下, 心筋/縦隔比の低下, クリアランスの亢進という異常所見が認められた. さらに, これらの異常所見は腫瘍摘出術後に改善した. 本症例における術前の123I-MIBGの心臓動態の異常は, 心筋障害の反映としての心臓交感神経機能異常ではなく, 血中カテコールアミンの高値と関連する現象と推定された. 各種心疾患における123I-MIBG心筋シンチグラムの異常所見の発現機序は不明な点が多いが, 本症例の摘出術前後の123I-MIBG心筋シンチグラム所見は, 123I-MIBGの心臓における動態を解釈する上で貴重と考えられ報告した. |
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| Practice | 臨床医学：一般 |
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| Keywords | Pheochromocytoma, 123I-MIBG, Cardiac sympathetic nerve function, Catecholamine. |
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| English |
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| Title | 123I-Metaiodobenzylguanidine Myocardial Scintigraphy in a Case of Pheochromocytoma before and after Resection of It |
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| Authors | Katsushige MATSUMOTO*, Hiroki SUGIHARA**, Kazuki ITO*, Kouji TERADA*, Yoko TANIGUCHI*, Katsuichi OHTSUKI*, Tetsuo NAKATA*, Yo USHIJIMA**, Tomoho MAEDA**, Masao NAKAGAWA* |
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| Authors(kana) | |
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| Organization | *Second Department of Medicine, **Department of Radiology, Kyoto Prefectural University of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 9 |
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| Page | 1023-1028 |
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| Year/Month | 1995/9 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | A 55-year-old man with pheochromocytoma was examined by 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy before and after resection of the tumor. MIBG images showed decreased uptake in infero-posterior wall before operation. The heart to upper mediastinum uptake ratio was low at the delayed anterior planar image, and mean MIBG clearance from the left ventricle was increased. These abnormal scintigraphic findings improved after resection of the tumor. We thought that these abnormal MIBG findings were not due to abnormal cardiac sympathetic nerve function, because ECG, chest X-ray, UCG and 201Tl myocardial scintigram did not reveal any abnormality. It may be presumed that these abnormal MIBG findings were caused by high plasma catecholamines concentration. The mechanism of abnormal MIBG findings of the heart remains uncertain in various heart diseases. MIBG findings in this case with pheochromocytoma before and after resection may contribute to interpretation of the kinetics of MIBG in heart. |
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| Practice | Clinical medicine |
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| Keywords | Pheochromocytoma, 123I-MIBG, Cardiac sympathetic nerve function, Catecholamine. |
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