| Japanese |
|---|
| Title | ジピリダモール負荷99mTc-tetrofosmin心筋シンチグラフィの臨床的検討 |
|---|
| Subtitle | 原著 |
|---|
| Authors | 足立至*, 杉岡靖*, 田渕耕次郎*, 難波隆一郎*, 中田和伸*, 西垣洋*, 松井律夫*, 末吉公三*, 楢林勇*, 大久保知之**, 田本重美**, 大竹義章*** |
|---|
| Authors(kana) | |
|---|
| Organization | *大阪医科大学放射線科, **第一内科, ***第三内科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 32 |
|---|
| Number | 9 |
|---|
| Page | 943-951 |
|---|
| Year/Month | 1995/9 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」新しい99mTc心筋血流製剤である99mTc-tetrofosminを使用し, ジピリダモール負荷心筋シンチグラフィの可能性について検討した. 107症例に1日法で施行し, 得られた心筋SPECT像と心筋と肝臓との重なりについて画質評価を行い, そのうちの55症例は心血管造影所見と対比検討した. 負荷時早期像は99mTc-tetrofosminを259MBq投与し, 45分以上の間隔で撮影すれば最適な心筋SPECT像を得ることができた. 安静時遅延像では555MBqを投与し1時間以上の間隔で撮影し, 全例で良好な心筋SPECT像が得られた. 心血管造影の壁運動異常の対比では, 異常のない区域ではすべて壁運動異常がなく, 心筋集積の低下した区域のうち77%の区域で壁運動異常がみられた. 冠動脈造影では87%で一致した. 以上から99mTc-tetrofosminを使用しても, ジピリダモール負荷心筋シンチグラフィは1日法で可能であり, 201Tlと同等もしくはそれ以上の診断能を有する検査法と考えられた. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Dipyridamole, 99mTc-tetrofosmin, Coronary artery disease, Myocardial scintigraphy. |
|---|
| English |
|---|
| Title | Clinical Usefulness of Dipyridamole Loading 99mTc-Tetrofosmin Myocardial Scintigraphy |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Itaru ADACHI*, Yasushi SUGIOKA*, Koujirou TABUCHI*, Ryuuichirou NAMBA*, Yasunobu NAKATA*, Hiroshi NISHIGAKI*, Ritsuo MATSUI*, Kouzou SUEYOSHI*, Isamu NARABAYASHI*, Tomoyuki OHKUBO**, Shigemi TAMOTO**, Yoshiaki OHTAKE*** |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology, **First Department of Internal Medicine, ***Third Department of Internal Medicine, Osaka Medical College |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 32 |
|---|
| Number | 9 |
|---|
| Page | 943-951 |
|---|
| Year/Month | 1995/9 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | This study performed to establish the most suitable method in one-day protocol and to evaluate clinical usefulness of 99mTc-tetrofosmin myocardial scintigraphy after dipyridamole infusion. Image quality and liver overlapping of the myocardial SPECT were evaluated in 107 patients with old myocardial infarction (42 cases), angina pectoris (53 cases) and others (12 cases). Left ventricular wall motion and coronary artery stenosis were compared to myocardial uptake score in 55 patients who received cardiac catheterization. The suitable image quality was acquired in early SPECT images using 259 MBq of 99mTc-tetrofosmin. The overlapping between inferior wall and liver uptake was able to minimize over 45 minutes interval from injection of 99mTc-tetrofosmin to data acquisition. The segments of normal wall motion had no perfusion defect of the myocardial SPECT in all cases (100%(148/148)). The segments of abnormal wall motion had decreased myocardial uptake of the myocardial SPECT (77%(24/31)). The agreement between coronary artery stenosis and decreased myocardial uptake was 96% (24/25) in right coronary artery, 87% (26/30) in left anterior descending coronary artery and 83% (19/23) in left circumflex coronary artery. These data suggests that image quality of dipyridamole loading 99mTc-Tetrofosmin myocardial scintigraphy is excellent such as that of 201Tl myocardial scintigraphy. Myocardial perfusion in the 99mTc-tetrofosmin myocardial scintigraphy is good correlation to both left ventricular wall motion and coronary artery stenosis. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Dipyridamole, 99mTc-tetrofosmin, Coronary artery disease, Myocardial scintigraphy. |
|---|