Japanese
Title閉塞性動脈硬化症 (ASO) における運動負荷下肢201TlClシンチグラフィの有用性 - PTA前後の血流評価を含めて -
Subtitle原著
Authors木島鉄仁*, 汲田伸一郎*, 水村直*, 隈崎達夫*
Authors(kana)
Organization*日本医科大学放射線科
Journal核医学
Volume32
Number9
Page935-941
Year/Month1995/9
Article原著
Publisher日本核医学会
Abstract「要旨」今回われわれは閉塞性動脈硬化症(ASO)28症例に対し最大負荷時静注法による運動負荷下肢201TlCl(Tl)シンチグラフィを行った. 得られた全身背面像の左右の臀部, 大腿部, 下肢部, 足部に関心領域を設定し, 各部の患側/健側比を求めたところ, 足部では平均0.81で, 他部位より有意に(p<0.05)低い値を示した. 他部位では逆に患側に高集積を示す例が認められた. 15例に経皮的血管形成術(PTA)施行前後における比較を行ったところ, 足部の患側/健側比は有意に(p<0.005)改善した. また患側Tl集積亢進群は患側Tl集積非亢進群より有意に病悩期間が短かった(p<0.05). 足部は下肢虚血を鋭敏に反映し, 患側下肢Tl高集積は下肢虚血の亜急性期における末梢循環の代償性変化が関与している可能性が推測された. 本法はPTA前後の評価や病変検出に有用と考えられ, ASOの診断や経過観察にも用いることが可能と思われた.
Practice臨床医学：一般
Keywords201TlCl, Exercise leg perfusion scintigraphy, ASO, PTA, Reactive hyperemia.
English
TitleUsefulness of the 201TlCl Exercise Leg Perfusion Scintigraphy in Arteriosclerosis Obliterans (ASO) - With Evaluation of Leg Perfusion Comparing Before and After PTA -
SubtitleOriginal Articles
AuthorsTetsuji KIJIMA, Shin-ichiro KUMITA, Sunao MIZUMURA, Tatsuo KUMAZAKI
Authors(kana)
OrganizationDepartment of Radiology, Nippon Medical School
JournalThe Japanese Journal of nuclear medicine
Volume32
Number9
Page935-941
Year/Month1995/9
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractTwenty-eight patients of arteriosclerosis obliterans (ASO) complaining of intermittent claudication or pain at rest underwent symptom limited exercise leg perfusion scintigraghy using 201TlCl (Tl). Regions of interest (ROI) were drawn around each buttocks, thighs, calves and feet in whole body image, and we calculated Lesion/Normal Index (LNI) which was the devided value of the average count per pixel of each ROI of the affected side by that of the normal side. The average LNI of the foot was 0.81 and was smaller than other regions (p<0.05). Other region except foot showed Tl high uptake in affected side in some cases. Fifteen patients were compared after percutaneous transluminal angioplasty (PTA) with before PTA, and LNI of the foot was statistically improve after PTA (p<0.005). The period suffer from disease of the group of Tl hight uptake in the affected leg was statistically shorter than that of the group of Tl non-high uptake (p<0.05). We supposed that the Tl uptake of the foot reflects ischemia of the leg sensitively, and high uptake of Tl in affected leg is concerned with compensatory change of microcirculation of ischemic leg in subacute period. This scintigraphy was thought to be useful to detect the ASO and to evaluate the effect of PTA, and was able to avail diagnosis and observation of the course of ASO patient.
PracticeClinical medicine
Keywords201TlCl, Exercise leg perfusion scintigraphy, ASO, PTA, Reactive hyperemia.

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