| Japanese |
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| Title | 健常者における123I-BMIPPの臓器分布および心筋局所分布に関する検討 |
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| Subtitle | 原著 |
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| Authors | 竹内利治*, 井門明*, 柏木雄介*, 大井伸治*, 長谷部直幸*, 山下裕久*, 菊池健次郎*, 佐藤順一**, 石川幸雄** |
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| Organization | *旭川医科大学医学部第一内科, **放射線部 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 7 |
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| Page | 675-681 |
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| Year/Month | 1995/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」健常者(13例, 平均年齢43.9歳)における123I-BMIPPの心筋, 肺, 肝臓への臓器分布および心筋局所分布について検討した. Planar像での縦隔に対する心臓, 肺, 肝臓のカウント比は早期像でそれぞれ2.63, 1.28, 3.80と肝臓, 心臓, 肺の順に高値を示すのに対し, 後期像ではそれぞれ2.23, 1.20, 2.26と肝臓と心臓の取り込みはほぼ同等となった. SPECTでの左室前壁, 中隔, 後壁, 側壁の相対的カウントは早期像でそれぞれ100, 98, 96, 108(%), 後期像で100, 98, 99, 107(%)であり, ともに側壁で有意に高かった. また心基部, 中部, 心尖部の相対的カウントはそれぞれ早期像で100, 111, 87(%), 後期像で100, 113, 92(%)であり, 左室中部が最も高く, 心基部, 心尖部の順に低下し3部位間にいずれも有意差が認められた. 以上より123I-BMIPPの心筋局所分布は健常者において必ずしも均一ではないことが明らかとなり, 123I-BMIPPを心筋症の早期病変や軽度の心筋虚血などの検出に用いる際には, 特にこの点を十分に配慮することが重要と思われる. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-BMIPP(β-methyl-p-iodophenylpentadecanoic-acid), Normal subjects, Systemic distribution, Regional myocardial distribution. |
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| English |
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| Title | Systemic and Regional Myocardial Distribution of 123I-BMIPP in Normal Subjects |
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| Subtitle | Original Articles |
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| Authors | Toshiharu TAKEUCHI*, Akira IDO*, Yusuke KASHIWAGI*, Shinji OHI*, Naoyuki HASEBE*, Hirohisa YAMASHITA*, Kenjiro KIKUCHI*, Junichi SATO**, Yukio ISHIKAWA** |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, **Department of Radiology, Asahikawa Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 7 |
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| Page | 675-681 |
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| Year/Month | 1995/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We estimated the systemic and left ventricular (LV) regional myocardial distribution of 123I-BMIPP(β-methyl-p-iodophenyl-pentadecanoic-acid) in normal subjects (n=13, mean age 43.9). In planar studies, the count ratios of heart, lung and liver to mediastinum were 2.63, 1.28 and 3.80 in the early images, and 2.23, 1.20 and 2.26 in the delayed images, respectively. The uptake in liver was almost identical with that in heart in the delayed images. In SPECT studies, the regional relative counts in anterior, septal, posterior and lateral LV walls were 100, 98, 96 and 108 (%) in the initial images, and 100, 98, 99 and 107 (%) in the delayed images, respectively. The regional relative uptake was significantly higher in the lateral wall than those in the other parts of LV walls in both images. The relative counts in the basal, mid- and apical portions were 100, 111 and 87 (%) in the initial images, and 100, 113, 92 (%) in the delayed images, respectively. These results suggest that the myocardial regional distribution of BMIPP is not always uniform even in normal subjects. Thus, it is necessary to interpret with caution in the light of these findings, especially for detect in a myocardial lesion in an early phase of cardiomyopathy or a mild myocardial ischemia. |
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| Practice | Clinical medicine |
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| Keywords | 123I-BMIPP(β-methyl-p-iodophenylpentadecanoic-acid), Normal subjects, Systemic distribution, Regional myocardial distribution. |
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