| Japanese |
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| Title | 二次性副甲状腺機能亢進症患者における副甲状腺摘除術前後の骨塩量の変化 - 部位別の比較検討 - |
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| Subtitle | 原著 |
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| Authors | 小橋肇子*, 岡村光英**, 河辺譲治*, 細川知紗*, 池田裕子*, 小山孝一*, 萩原聡***, 武本佳昭****, 越智宏暢**, 山田龍作* |
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| Authors(kana) | |
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| Organization | *大阪市立大学医学部放射線科教室, **核医学研究室, ***第二内科学教室, ****泌尿器科教室 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 7 |
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| Page | 667-673 |
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| Year/Month | 1995/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」二次性副甲状腺機能亢進症(以下2°HPTと略す)をきたした血液透析患者で, 副甲状腺摘除術(以下PTXと略す)が施行された35例を対象に, PTX前後の骨塩量の変化を部位別(橈骨遠位部1/3, 頭部, 全身骨, 第3腰椎)に測定し比較検討した. 2°HPT患者の骨塩量はPTX前は健常者と比べ各部位で低値を示し, 特に皮質骨主体の橈骨が著明に低値であった. PTX後の骨塩量は, 各部位において増加を認め, 特に頭部での増加が顕著であった(PTX前に対し67%増加). また, 海綿骨が主体の腰椎の骨塩量は術後1年までは増加し(17%), 1年以降ではむしろ減少した(14%). 1年以降の減少は加齢による影響も加味されていると思われる. 橈骨骨塩量も頭部ほど顕著ではないが, 術後2年まで上昇し続けた(23.2%). 以上より, PTX後の骨塩量の変化は, 部位によって違いがあり, 治療効果の判定には, 最も鋭敏に反映する頭部の測定が有用と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Secondary hyperparathyroidism, Parathyroidectomy, Bone mineral density, Total bone mineral. |
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| English |
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| Title | Assessment of Bone Mineralization of Hemodialyzed Patients with SPA and DPA - Different Effect of PTX with the Site - |
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| Subtitle | Original Articles |
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| Authors | Toshiko KOBASHI*, Terue OKAMURA**, Joji KAWABE*, Chisa HOSOKAWA*, Hiroko IKEDA*, Koichi KOYAMA*, Satoshi HAGIWARA***, Yoshiaki TAKEMOTO****, Hironobu OCHI**, Ryusaku YAMADA* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Osaka City University Medical School, **Division of Nuclear Medicine, Osaka City University Medical School, ***Department of Second Internal Medicine, Osaka City University Medical School, ****Department of Urology, Osaka City University Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 7 |
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| Page | 667-673 |
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| Year/Month | 1995/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We analyzed the bone changes at each site of secondary hyperparathyroidism (2°HPT) on hemodialyzed patients using both single photon absorptiometry (SPA) and dual photon absorptiometry (DPA). The subjects were 35 hemodialysis patients (12 male, 24 female) with 2°HPT. The bone mineral densities (BMD) of 1/3 radius, head, total body and 3rd lumbar spine were measured before and after parathyroidectomy (PTX). Before PTX, the BMD of 2°HPT patients were lower than the normal range of all sites, especially at the radius which mainly consisted of cortical bone. After PTX, the BMD at all sites increased especially in the head. The BMD of the radius also continued to increased up two years after PTX, but it was not as increased as the BMD of head. The BMD of the lumber spine which consisted of cancellous bone mainly increased after PTX for one year and decreased thereafter. This decrease was influenced by age. There was a difference with the site of BMD after PTX. The determination of changes of BMD of head and radius was considered useful for the judgment of treatment. |
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| Practice | Clinical medicine |
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| Keywords | Secondary hyperparathyroidism, Parathyroidectomy, Bone mineral density, Total bone mineral. |
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