| Japanese |
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| Title | 123I-MIBG (metaiodobenzylguanidine) シンチグラム早期像による褐色細胞腫の診断 |
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| Subtitle | 原著 |
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| Authors | 石川演美*, 武田徹*, 呉勁*, 越後純子*, 板井悠二* |
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| Organization | *筑波大学臨床医学系 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 7 |
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| Page | 659-665 |
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| Year/Month | 1995/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」123I-MIBG(metaiodobenzylguanidine), 111MBqによるシンチグラム6時間早期像を撮像し, 褐色細胞腫の診断能について検討した. 組織病理学的に診断された褐色細胞腫9例では全例に集積し, 局在診断, 質的診断に有用であった. しかし皮質腺腫と診断された1例にも偽陽性を認めた. 検出された最小のものは直径3cmであった. 肝の集積残存は腫瘤の解剖学的位置関係の理解に有用であった. 褐色細胞腫の術後経過観察の5例では3例に骨, 頸部, 副腎への転移・再発を診断することができた. 発作性または動揺性高血圧のため, 異所性褐色細胞腫を疑われた10例では異常所見はなかった. 正常副腎への集積は45%に見られた. これらの結果から123I-MIBGシンチグラフィ早期像は精細な画像が得られるため腫瘤の内部状態や肝との位置関係を知ることができ, さらに短時間で結果をだすことが可能で, 臨床的に有用性が高いと結論された. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-MIBG, 131I-MIBG, Pheochromocytoma. |
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| English |
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| Title | The Efficacy of Early 123I-MIBG Scintigraphy for Pheochromocytoma Diagnosis |
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| Subtitle | Original Articles |
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| Authors | Nobuyoshi ISHIKAWA, Tohoru TAKEDA, Jin WU, Junko ECHIGO, Yuji ITAI |
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| Authors(kana) | |
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| Organization | Institute of Clinical Medicine, University of Tsukuba |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 7 |
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| Page | 659-665 |
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| Year/Month | 1995/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | Early scintigraphy, that obtained 6 hours after intravenous administration of a low dose of 123I-metaiodobenzylguanidine (111 MBq) was evaluated for diagnostic efficacy. The accumulation of 123I-MIBG in the tumor masses of nine patients with pheochromocytoma and one patient with cortical adenoma were noted. The smallest pheochromocytoma visualized was 3 cm in diameter. The hepatic uptake of this radiolabeled compound was helpful to understand the anatomical position of the abnormal uptake. Three of five postoperative cases of pheochromocytoma showed uptake in the metastasis in the skeleton or recurrences in the neck or contralateral adrenal gland. No ectopic pheochromocytoma was found in the pelvic cavity. Faint accumulation in the normal medulla was noted in 45% of the cases. The present results demonstrate that superior images can be obtained in scintigrams takes 6 hours after administration of a lower dose of 123I-MIBG. |
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| Practice | Clinical medicine |
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| Keywords | 123I-MIBG, 131I-MIBG, Pheochromocytoma. |
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