| Japanese |
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| Title | 心電図同期99mTc-MIBI SPECTによる左室壁肥厚評価 - Normal fileの有用性 - |
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| Subtitle | 原著 |
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| Authors | 白川誠士*, 服部直也**, 玉木長良**, 藤田透*, 矢野慎輔*, 工藤崇**, 米倉義晴***, 小西淳二** |
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| Authors(kana) | |
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| Organization | *京都大学医学部附属病院放射線部, **核医学科, ***京都大学医学部脳病態生理学講座 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 7 |
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| Page | 643-650 |
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| Year/Month | 1995/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」99mTc-methoxy isobutyl isonitrile(MIBI)を用いた心電図同期SPECTにおいて, 拡張末期(ED)から収縮末期(ES)へのカウントの増加度より左室壁肥厚評価が可能である. 今回の検討は, (ES count-ED count)/ED count×100に基づいた%Thickening値において正常者の左室壁肥厚評価を行った. 心疾患の既往のない20例を対象とし, 心電図同期SPECTを99mTc-MIBI 600 MBq投与3時間後より施行した. 収集した投影データより画像再構成を行いED, ESおよび%Thickeningを同心円表示しnormal fileを作成した. 血流分布ではED, ESともに前壁から側壁にかけて高カウント域が存在し, 正常者においても均一な分布は得られなかった. %Thickeningについても心尖部で高値, 前壁, 側壁, 中隔では低値を示し, 区域ごとに異なる値を示した. また, 男女間においても有意差が認められた. 以上より, 壁肥厚の定量的評価には対比するnormal file作成の必要性が示唆された. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-MIBI, Gated SPECT, % Thickening, Normal file. |
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| English |
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| Title | Assessment of Left Ventricular Wall Thickening with Gated 99mTc-MIBI SPECT - Value of Normal File - |
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| Subtitle | Original Articles |
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| Authors | Seiji SHIRAKAWA*, Naoya HATTORI**, Nagara TAMAKI**, Toru FUJITA*, Shinsuke YANO*, Takashi KUDOH**, Yoshiharu YONEKURA***, Junji KONISHI** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Department of Nuclear Medicine, ***Department of Brain Pathophysiology, Kyoto University Faculty of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 7 |
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| Page | 643-650 |
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| Year/Month | 1995/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | The wall thickening was assessed by regional count increase from end-diastole (ED) to end-systole (ES) in gated 99mTc-MIBI SPECT. The wall thickening index was calculated as (ES count-ED count)/ED count×100(% thickening). Gated SPECT was performed three hours after injection of 600 MBq of 99mTc-MIBI in 20 normal subjects to create normal files (ED, ES perfusion maps and % thickening map). In normal ED and ES perfusion maps, distribution in anterior and lateral regions were higher than other regions, indicating heterogeneous perfusion. In addition, the % thickening in apex was higher than anterior and lateral and septal regions, suggesting heterogeneous % thickening in normal subjects. Furthermore, the % thickening was different between male and female. We conclude that quantitative analysis of regional thickening can be performed by gated 99mTc-MIBI SPECT with normal files. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-MIBI, Gated SPECT, % Thickening, Normal file. |
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