| Japanese |
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| Title | 安定および不安定狭心症における123I-BMIPP心筋シンチグラフィの臨床的意義 |
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| Subtitle | 原著 |
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| Authors | 井上征治*, 小林秀樹**, 岡俊明*, 河口正雄*, 百瀬満**, 笠貫宏*, 日下部きよ子**, 細田瑳一* |
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| Authors(kana) | |
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| Organization | *東京女子医科大学日本心臓血圧研究所循環器内科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 7 |
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| Page | 625-630 |
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| Year/Month | 1995/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」労作性狭心症における123I-BMIPP心筋シンチグラフィ(BMIPP)の臨床的有用性について不安定狭心症と対比して検討した. 労作性狭心症33例を対象に安静BMIPPと運動負荷201TlCl心筋シンチグラフィ(Tl)を, また増悪型不安定狭心症13例に対し, 安静BMIPPと安静Tlを施行した. SPECT像は心筋を14セグメントに分割して評価した. 労作性狭心症の心筋虚血282セグメント中のBMIPPとTl負荷像のRI集積一致率は45%であり, Tl負荷像の集積低下スコアが最も高かった. 不安定狭心症の虚血62セグメント中のBMIPPとTl安静像の一致率は32%で, BMIPP像の集積低下スコアがTl像より高かった. 壁運動低下と各画像のRI集積低下を比較するとBMIPPとの相関(r=0.71)が良好であった. 狭心症においてBMIPPの集積低下を認める虚血部位は, 心筋代謝が変化し, 壁運動異常を伴う場合があり, 虚血としてより重症と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Beta-methyl-iodophenylpentadecanoic acid (BMIPP), Stable effort angina pectoris, Unstable angina pectoris, Left ventricular wall motion. |
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| English |
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| Title | Usefulness of 123I-BMIPP Myocardial Imaging in Patients with Stable Effort Angina and Unstable Angina |
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| Subtitle | Original Articles |
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| Authors | Seiji INOUE*, Hideki KOBAYASHI**, Toshiaki OKA*, Masao KAWAGUCHI*, Mitsuru MOMOSE**, Hiroshi KASANUKI*, Kiyoko KUSAKABE**, Saichi HOSODA* |
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| Authors(kana) | |
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| Organization | *Department of Cardiology, The Heart Institute of Japan, Tokyo Women's Medical College, **Department of Radiology, Tokyo Women's Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 7 |
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| Page | 625-630 |
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| Year/Month | 1995/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We evaluated the clinical significance of myocardial imaging using 123I-15-(p-iodophenyl)-3-methyl pentadecanoic acid (BMIPP) scintigraphy in patients with stable effort angina pectoris (SAP) and unstable angina pectoris (UAP). Thirty-three patients with SAP were studied using rest BMIPP and stress 201TlCl (Tl) myocardial scintigraphy, and 13 patients with worsening effort type of UAP were also examined using both rest BMIPP and Tl scintigraphy. We compared those BMIPP findings with myocardial perfusion images obtained with Tl and the regional wall motion determined by left ventriculography. In 45% of 282 segments of myocardial ischemia of SAP, the degree of myocardial uptake of BMIPP was concordant with that of stress Tl and the defect score of Tl was higher than that of BMIPP. On the other hand, in 32% of 62 segments of ischemia of UAP, the degree of myocardial BMIPP and Tl uptake was concordant and BMIPP defect score was higher than Tl score. In SAP, the decrease in regional wall motion agreed better with the decrease in myocardial uptake of BMIPP than that of Tl. These results suggest that myocardial ischemic regions decreased BMIPP uptake show the disturbance of fatty acid metabolism and lead to abnormal wall motions. Such ischemic regions may be clinically severe state in patients with angina pectoris. |
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| Practice | Clinical medicine |
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| Keywords | Beta-methyl-iodophenylpentadecanoic acid (BMIPP), Stable effort angina pectoris, Unstable angina pectoris, Left ventricular wall motion. |
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